Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 9/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32679237 | 1.00 | GRM5 (0.45) | GRM5APPADORA2APDGFRBPDGFRA | |
| SCHEMBL32679238 | 1.00 | GRM5 (0.45) | GRM5APPADORA2APDGFRBPDGFRA | |
| SCHEMBL14843225 | 0.77 | PDGFRB (0.47) | GRM5PDGFRBPDGFRAKDM4EEGFR | |
| SCHEMBL223540 | 0.75 | CYP1A2 (0.43) | GRM5HTR3AHRH4KDM4EGPR3 | |
| SCHEMBL30824520 | 0.75 | KDM4E (0.42) | GRM5HTR3AHRH4KDM4EGPR3 | |
| SCHEMBL2773608 | 0.75 | KDM4E (0.42) | GRM5HTR3AHRH4KDM4EGPR3 | |
| SCHEMBL29947454 | 0.75 | ALDH1A1 (0.43) | HTR3AHRH4KDM4EGPR3EGFR | |
| SCHEMBL6005051 | 0.75 | KDM4E (0.42) | GRM5HTR3AHRH4KDM4EGPR3 | |
| SCHEMBL1996212 | 0.75 | ALDH1A1 (0.43) | HTR3AHRH4KDM4EGPR3EGFR | |
| SCHEMBL7548858 | 0.75 | KDM4E (0.42) | GRM5HTR3AHRH4KDM4EGPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121574132-A | Pyrrolo [2,1-b ] quinazoline-9 (1H) -one derivative and application thereof | 安阳工学院 | 2026-02-27 | — | — | CN | disclosed |