Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 6/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.38 |
| ▸ | BACE2 | Q9Y5Z0 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7277577 | 1.00 | CTSC (0.41) | CTSCBACE1KLK7CTSLOPRM1 | |
| SCHEMBL15099494 | 0.86 | CTSC (0.48) | CTSCBACE1OPRM1OPRL1TSHR | |
| SCHEMBL8693462 | 0.86 | CTSC (0.48) | CTSCBACE1OPRM1OPRL1TSHR | |
| SCHEMBL8690915 | 0.86 | CTSC (0.48) | CTSCBACE1OPRM1OPRL1TSHR | |
| Hydrochloric Acid SCHEMBL7323379 | 0.85 | CTSC (0.47) | CTSCBACE1OPRM1OPRL1TSHR | |
| Hydrochloric Acid SCHEMBL3053757 | 0.85 | CTSC (0.47) | CTSCBACE1OPRM1OPRL1TSHR | |
| SCHEMBL7798759 | 0.84 | OPRM1 (0.39) | CTSCBACE1OPRM1OPRL1ABCB1 | |
| SCHEMBL16920332 | 0.84 | ACACB (0.37) | KMT2A | |
| SCHEMBL23371636 | 0.83 | CTSC (0.45) | CTSCCTSLOPRM1OPRL1TSHR | |
| SCHEMBL12161925 | 0.83 | CTSC (0.45) | CTSCCTSLOPRM1OPRL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101300228-B | Process for production of benzyloxypyrrolidine derivative, and process for production of hydrochloride salt powder of optically active benzyloxypyrrolidine derivative | TORAY FINECHEMICALS CO LTD | 2013-05-08 | — | — | CN | disclosed |
| CN-101400668-A | 2-(cyclic amino)-pyrimidone derivatives as TPK1 inhibitors | MITSUBISHI PHARMA CORP (JP) | 2009-04-01 | — | — | CN | disclosed |
| CN-101300228-A | Process for production of benzyloxypyrrolidine derivative, and process for production of hydrochloride salt powder of optically active benzyloxypyrrolidine derivative | TORAY FINECHEMICALS CO LTD (JP) | 2008-11-05 | — | — | CN | disclosed |