Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | CTSC | P53634 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27736155 | 0.84 | CTSC (0.41) | OPRM1OPRL1L3MBTL1CTSCABCB1 | |
| SCHEMBL7277577 | 0.84 | CTSC (0.41) | OPRM1OPRL1L3MBTL1CTSCABCB1 | |
| SCHEMBL7863488 | 0.81 | ABCB1 (0.36) | L3MBTL1CTSCABCB1BACE1 | |
| SCHEMBL7880855 | 0.81 | ABCB1 (0.36) | L3MBTL1CTSCABCB1BACE1 | |
| SCHEMBL7809312 | 0.81 | SIGMAR1 (0.39) | OPRM1OPRL1L3MBTL1CTSCHTR2C | |
| SCHEMBL7806166 | 0.80 | ALDH1A1 (0.39) | L3MBTL1CTSCBACE1HTR2C | |
| SCHEMBL7807821 | 0.79 | SIGMAR1 (0.39) | OPRM1OPRL1CTSCHTR2C | |
| SCHEMBL7805186 | 0.79 | CTSC (0.48) | CTSCABCB1HTR2C | |
| SCHEMBL8098831 | 0.78 | L3MBTL1 (0.38) | OPRM1OPRL1L3MBTL1ABCB1BACE1 | |
| SCHEMBL8690915 | 0.78 | CTSC (0.48) | OPRM1OPRL1CTSCBACE1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1155013-A1 | HETEROCYCLIC BENZENESULPHONAMIDE COMPOUNDS AS BRADYKININE ANTAGONISTS | FOURNIER INDUSTRIE ET SANTE (FR) | 2001-11-21 | — | — | EP | disclosed |
| WO-2000050418-A1 | HETEROCYCLIC BENZENESULPHONAMIDE COMPOUNDS AS BRADYKININE ANTAGONISTS | FOURNIER INDUSTRIE ET SANTE (FR) | 2000-08-31 | — | — | WO | disclosed |