Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 1/20 | 0.56 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.56 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | TPMT | P51580 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SELL | P14151 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL9614895 | 0.86 | PLAU (0.55) | CA12CA1CA2CA7CA9 | |
| Gallic Acid SCHEMBL4126178 | 0.84 | KDM4E (0.74) | GLRA1SLC6A9OR51E2CA12CA1 | |
| Terephthalic Acid SCHEMBL10582137 | 0.83 | TSHR (0.67) | GLRA1SLC6A9OR51E2CA12CA1 | |
| Hydrazine SCHEMBL29046518 | 0.82 | CA12 (0.58) | CA12CA1CA2CA7CA9 | |
| SCHEMBL26189 | 0.82 | CA12 (0.65) | CA12CA1CA2CA7CA9 | |
| SCHEMBL22982 | 0.82 | CA12 (0.65) | CA12CA1CA2CA7CA9 | |
| Urea SCHEMBL28872578 | 0.79 | CA12 (0.55) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10743704 | 0.79 | CA12 (0.48) | CA12CA1CA2CA7CA9 | |
| Benzoic Acid SCHEMBL1573399 | 0.79 | TSHR (0.70) | GLRA1SLC6A9OR51E2TP53KDM4E | |
| SCHEMBL934326 | 0.79 | LOXL2 (0.44) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101404886-A | Aqueous suspension concentrate | BAYER CROPSCIENCE AG (DE) | 2009-04-08 | — | — | CN | disclosed |