Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA7 | P43166 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CA3 | P07451 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | SELL | P14151 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | SELP | P16109 | 1/20 | 0.55 |
| ▸ | FUT4 | P22083 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
| ▸ | DPP4 | P27487 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10743704 | 0.87 | CA12 (0.48) | PLAUCA12CA1CA2CA7 | |
| Glycine SCHEMBL27736637 | 0.86 | GLRA1 (0.56) | PLAUCA12CA1CA2CA7 | |
| Gallic Acid SCHEMBL5427564 | 0.85 | KDM4E (0.81) | PLAUCA12CA1CA2CA7 | |
| Hydrazine SCHEMBL29046518 | 0.84 | CA12 (0.58) | CA12CA1CA2CA7CA9 | |
| SCHEMBL22982 | 0.84 | CA12 (0.65) | CA12CA1CA2CA7CA9 | |
| SCHEMBL26189 | 0.84 | CA12 (0.65) | CA12CA1CA2CA7CA9 | |
| Terephthalic Acid SCHEMBL29181739 | 0.82 | TSHR (0.71) | CA12CA1CA2CA7CA9 | |
| Urea SCHEMBL28872578 | 0.81 | CA12 (0.55) | CA12CA1CA2CA7CA9 | |
| SCHEMBL934326 | 0.81 | LOXL2 (0.44) | PLAUCA12CA1CA2CA7 | |
| SCHEMBL23004950 | 0.81 | CA12 (0.61) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106795388-A | Coating liquid, coated film and composite | 大日精化工业株式会社 | 2017-05-31 | — | — | CN | disclosed |
| EP-0504183-A1 | POWDER COATINGS BASED ON EPOXY RESINS. | SWAN THOMAS & CO LTD (GB) | 1992-09-23 | — | — | EP | disclosed |
| WO-1991008268-A1 | POWDER COATINGS BASED ON EPOXY RESINS | THOMAS SWAN & CO., LTD. (GB) | 1991-06-13 | — | — | WO | disclosed |