Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 7/20 | 0.56 |
| ▸ | WNT3A | P56704 | 7/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.46 |
| ▸ | CLK2 | P49760 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.46 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | SGK2 | Q9HBY8 | 1/20 | 0.46 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL261380 | 0.91 | CTNNB1 (0.65) | CTNNB1WNT3ANPC1RAB9AJAK2 | |
| SCHEMBL30270547 | 0.91 | CTNNB1 (0.65) | CTNNB1WNT3ANPC1RAB9AJAK2 | |
| Hydrochloric Acid SCHEMBL1665151 | 0.89 | CTNNB1 (0.63) | CTNNB1WNT3ANPC1RAB9AJAK2 | |
| Trifluoroacetic Acid SCHEMBL18108738 | 0.88 | AR (0.54) | CTNNB1WNT3ANPC1RAB9AJAK2 | |
| Trifluoroacetic Acid SCHEMBL18108734 | 0.88 | AR (0.54) | CTNNB1WNT3ANPC1RAB9AJAK2 | |
| Trifluoroacetic Acid SCHEMBL2555084 | 0.82 | ROCK2 (0.70) | CTNNB1WNT3ANPC1RAB9AJAK2 | |
| Trifluoroacetic Acid SCHEMBL5404493 | 0.79 | SMYD3 (0.58) | ROCK2ROCK1 | |
| Trifluoroacetic Acid SCHEMBL5404490 | 0.79 | SMYD3 (0.58) | ROCK2ROCK1 | |
| SCHEMBL23063810 | 0.78 | GSK3B (0.68) | CTNNB1WNT3ANPC1RAB9AJAK2 | |
| SCHEMBL31253099 | 0.78 | GSK3B (0.68) | CTNNB1WNT3ANPC1RAB9AJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101203518-B | Fluorene derivative, composition containing the same and use thereof | AVENTIS PHARMA SA | 2013-07-24 | — | — | CN | claimed |
| CN-101203518-A | Novel fluorene derivatives, compositions containing same and uses thereof | AVENTIS PHARMA SA (FR) | 2008-06-18 | — | — | CN | claimed |
| CN-101203518-B | Fluorene derivative, composition containing the same and use thereof | AVENTIS PHARMA SA | 2013-07-24 | — | — | CN | disclosed |
| CN-101203518-A | Novel fluorene derivatives, compositions containing same and uses thereof | AVENTIS PHARMA SA (FR) | 2008-06-18 | — | — | CN | disclosed |