Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | DDO | Q99489 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2074995 | 0.80 | AHR (0.47) | AHRALDH1A1TSHRHTTKDM4E | |
| SCHEMBL3482864 | 0.77 | ALDH1A1 (0.44) | AHRALDH1A1TSHRHTTKDM4E | |
| SCHEMBL3483297 | 0.75 | SMN1; SMN2 (0.41) | ALDH1A1HTTKDM4EGAAMAPT | |
| SCHEMBL9539762 | 0.74 | HTT (0.47) | AHRALDH1A1TSHRHTTKDM4E | |
| SCHEMBL2388664 | 0.74 | ALDH1A1 (0.39) | AHRALDH1A1HTTKDM4EHPGD | |
| SCHEMBL3483178 | 0.68 | ALDH1A1 (0.40) | ALDH1A1TSHRHTTKDM4EHPGD | |
| SCHEMBL3078539 | 0.67 | HTT (0.38) | ALDH1A1TSHRHTTKDM4EPOLB | |
| SCHEMBL3924204 | 0.67 | AHR (0.61) | AHRDAODDOALDH1A1TSHR | |
| SCHEMBL9538070 | 0.67 | HTT (0.30) | HTTHSD17B10 | |
| SCHEMBL24817 | 0.65 | ALDH1A1 (0.54) | AHRALDH1A1HTTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101410366-A | Substituted bicyclic ring derivatives and uses thereof | ASAHI KASEI PHARMA CORP (JP) | 2009-04-15 | — | — | CN | disclosed |