Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29381779 | 0.98 | POLB (0.51) | POLBMAPTMEN1KMT2APIN1 | |
| SCHEMBL202663 | 0.98 | POLB (0.51) | POLBMAPTMEN1KMT2APIN1 | |
| Hydrochloric Acid SCHEMBL3867195 | 0.97 | POLB (0.50) | POLBMAPTMEN1KMT2APIN1 | |
| SCHEMBL31197366 | 0.97 | POLB (0.50) | POLBMAPTMEN1KMT2APIN1 | |
| SCHEMBL15923787 | 0.92 | POLB (0.46) | POLBMAPTMEN1KMT2APIN1 | |
| SCHEMBL6214746 | 0.83 | CYP1A2 (0.41) | POLBMAPTMEN1KMT2APIN1 | |
| SCHEMBL405386 | 0.82 | TSHR (0.47) | POLBMAPTMEN1KMT2ATSHR | |
| SCHEMBL29742161 | 0.82 | TSHR (0.47) | POLBMAPTMEN1KMT2ATSHR | |
| SCHEMBL15923304 | 0.80 | MAPT (0.40) | POLBMAPTMEN1KMT2APIN1 | |
| SCHEMBL16512770 | 0.80 | PIN1 (0.48) | MAPTMEN1KMT2APIN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101410114-B | A3 adenosine receptor allosteric modulators | US GOV HEALTH & HUMAN SERV (US) | 2012-07-04 | — | — | CN | disclosed |
| CN-101410114-A | A3 adenosine receptor allosteric modulators | US GOV HEALTH & HUMAN SERV (US) | 2009-04-15 | — | — | CN | disclosed |