Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4826614 | 0.92 | CYP1A2 (0.47) | CYP1A2TSHRFBP1POLBPIN1 | |
| SCHEMBL202663 | 0.84 | POLB (0.51) | CYP1A2TSHRPOLBPIN1MAPT | |
| SCHEMBL29381779 | 0.84 | POLB (0.51) | CYP1A2TSHRPOLBPIN1MAPT | |
| Ammonia Solution, Strong SCHEMBL27736895 | 0.83 | POLB (0.50) | CYP1A2TSHRPOLBPIN1MAPT | |
| Hydrochloric Acid SCHEMBL3867195 | 0.83 | POLB (0.50) | CYP1A2TSHRPOLBPIN1MAPT | |
| SCHEMBL31197366 | 0.83 | POLB (0.50) | CYP1A2TSHRPOLBPIN1MAPT | |
| SCHEMBL15923304 | 0.80 | MAPT (0.40) | POLBPIN1MAPTMEN1KMT2A | |
| SCHEMBL15923787 | 0.79 | POLB (0.46) | CYP1A2TSHRPOLBPIN1MAPT | |
| SCHEMBL8569400 | 0.77 | TSHR (0.50) | CYP1A2TSHRPOLBPIN1MAPT | |
| SCHEMBL15150627 | 0.74 | CYP1A2 (0.50) | CYP1A2TSHRPOLBMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1543002-A1 | PREPARATION OF 1H-IMIDAZO 4,5-C]QUINOLIN-4-AMINES VIA1H-IMIDAZO 4,5-C]QUINOLIN-4-PHTHALIMIDE INTERMEDIATES | BIOGAL GYOGYSZERGYAR RT. (HU) | 2005-06-22 | — | — | EP | disclosed |
| EP-1539752-A1 | PREPARATION OF 1H-IMIDAZO 4,5-C QUINOLIN-4-AMINES VIA NOVEL 1H-IMIDAZO 4,5-C QUINOLIN-4-CYANO AND 1H-IMIDA ZO 4,5-C QUINOLIN-4-CARBOXAMIDE INTERMEDIATES | BIOGAL GYOGYSZERGYAR RT. (HU) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004011462-A1 | PREPARATION OF 1H-IMIDAZO [4,5-C] QUINOLIN-4-AMINES VIA NOVEL 1H-IMIDAZO [4,5-C] QUINOLIN-4-CYANO AND 1H-IMIDAZO [4,5-C] QUINOLIN-4-CARBOXAMIDE INTERMEDIATES | BIOGAL GYOGYSZERGYAR RT. (HU) | 2004-02-05 | — | — | WO | disclosed |
| WO-2004009593-A1 | PREPARATION OF 1H-IMIDAZO[4,5-C]QUINOLIN-4-AMINES VIA1H-IMIDAZO [4,5-C]QUINOLIN-4-PHTHALIMIDE INTERMEDIATES | BIOGAL GYOGYSZERGYAR RT. (HU) | 2004-01-29 | — | — | WO | disclosed |