Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 16/20 | 0.70 |
| ▸ | FYN | P06241 | 2/20 | 0.60 |
| ▸ | SRC | P12931 | 2/20 | 0.60 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.58 |
| ▸ | CSF1R | P07333 | 2/20 | 0.54 |
| ▸ | VCP | P55072 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27737756 | 0.91 | EGFR (0.83) | EGFRFYNSRCERBB2VCP | |
| SCHEMBL5928094 | 0.85 | SRC (0.82) | EGFRFYNSRCERBB2VCP | |
| SCHEMBL6162947 | 0.82 | KDR (0.74) | EGFRSRC | |
| SCHEMBL6162938 | 0.82 | KDR (0.74) | EGFRSRC | |
| SCHEMBL28808048 | 0.82 | EGFR (0.82) | EGFRFYNSRCERBB2CSF1R | |
| SCHEMBL27758517 | 0.81 | EGFR (0.76) | EGFRFYNSRCERBB2CSF1R | |
| SCHEMBL27758535 | 0.80 | AURKB (0.68) | EGFRFYNSRCCSF1R | |
| SCHEMBL2998542 | 0.78 | EGFR (0.85) | EGFRFYNSRCERBB2 | |
| SCHEMBL2998538 | 0.78 | EGFR (0.85) | EGFRFYNSRCERBB2 | |
| SCHEMBL7237852 | 0.78 | SRC (0.71) | EGFRFYNSRCERBB2VCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101402611-A | Compound with anti-leukocythemia liveness and method of preparing the same | UNIV GUANGDONG PHARM (CN) | 2009-04-08 | — | — | CN | disclosed |