Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | MCOLN3 | Q8TDD5 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27716799 | 0.86 | LMNA (0.40) | LMNASMN1; SMN2MCOLN3TSHRMEN1 | |
| SCHEMBL27716802 | 0.86 | LMNA (0.42) | LMNASMN1; SMN2MCOLN3TSHRMEN1 | |
| SCHEMBL28771355 | 0.84 | LMNA (0.59) | LMNASMN1; SMN2MCOLN3TSHRCYP2C19 | |
| SCHEMBL28775617 | 0.83 | LMNA (0.40) | LMNASMN1; SMN2MCOLN3TSHRMEN1 | |
| SCHEMBL77762 | 0.73 | LMNA (0.62) | LMNASMN1; SMN2MCOLN3TSHRMEN1 | |
| SCHEMBL2518910 | 0.73 | LMNA (1.00) | LMNASMN1; SMN2MCOLN3TSHRMEN1 | |
| SCHEMBL27716801 | 0.72 | MAPT (0.41) | LMNAMEN1KMT2ACYP2C19ALDH1A1 | |
| SCHEMBL27716800 | 0.72 | KMT2A (0.43) | LMNAMCOLN3MEN1KMT2ACYP2C19 | |
| SCHEMBL79126 | 0.71 | LMNA (0.62) | LMNASMN1; SMN2MCOLN3TSHRMEN1 | |
| SCHEMBL28771354 | 0.70 | ALDH1A1 (0.40) | LMNAMCOLN3MEN1KMT2ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101223195-B | Transition metal complexes, catalyst compositions containing the same, and olefin polymerization using the catalyst compositions | LG CHEMICAL LTD | 2011-10-26 | — | — | CN | disclosed |
| CN-101223195-A | Transition metal complexes, catalyst compositions containing the same, and olefin polymerization using the catalyst compositions | LG CHEMICAL LTD (KR) | 2008-07-16 | — | — | CN | disclosed |