Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 10/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3080374 | 0.64 | CHRM5 (0.41) | TSHRCHRM5CHRM2CHRM4CHRM1 | |
| SCHEMBL5787127 | 0.63 | CHRM5 (0.54) | TSHRMETAP1CHRM5CHRM2CHRM4 | |
| SCHEMBL16450885 | 0.62 | SIGMAR1 (0.42) | TSHRCHRM5CHRM2CHRM4CHRM1 | |
| SCHEMBL6972069 | 0.62 | HRH3 (0.39) | METAP1CHRM5CHRM2CHRM4CHRM1 | |
| SCHEMBL6972067 | 0.62 | HRH3 (0.39) | METAP1CHRM5CHRM2CHRM4CHRM1 | |
| SCHEMBL5961386 | 0.62 | CYP1A2 (0.68) | CHRM5ADRA2CHRH3CYP1A2 | |
| SCHEMBL12568585 | 0.62 | CYP1A2 (0.62) | CHRM5ADRA2CHRH3CYP1A2 | |
| SCHEMBL9927939 | 0.62 | CYP1A2 (0.68) | CHRM5ADRA2CHRH3CYP1A2 | |
| SCHEMBL12568588 | 0.62 | CYP1A2 (0.68) | CHRM5ADRA2CHRH3CYP1A2 | |
| SCHEMBL4718925 | 0.62 | CYP1A2 (0.62) | CHRM5ADRA2CHRH3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101296902-A | Compounds comprising lactam or lactam derivative moieties, processes for preparing them and their use | UCB PHARMA SA (BE) | 2008-10-29 | — | — | CN | disclosed |