Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | METAP1 | P53582 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972067 | 1.00 | HRH3 (0.39) | HRH3KMT2AOPRK1METAP1KCNH2 | |
| SCHEMBL7561265 | 0.74 | ITGB1 (0.41) | — | |
| SCHEMBL6686977 | 0.72 | POLB (0.36) | HRH3KMT2A | |
| SCHEMBL6967927 | 0.68 | ITGB1 (0.37) | — | |
| SCHEMBL6967928 | 0.68 | ITGB1 (0.37) | — | |
| SCHEMBL248703 | 0.68 | MME (0.43) | KMT2A | |
| SCHEMBL6689324 | 0.68 | CA12 (0.47) | KMT2A | |
| SCHEMBL18497618 | 0.67 | HRH3 (0.46) | HRH3OPRK1KCNH2 | |
| SCHEMBL18497582 | 0.67 | HRH3 (0.46) | HRH3OPRK1KCNH2 | |
| SCHEMBL18497580 | 0.67 | HRH3 (0.46) | HRH3OPRK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023265-B1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF HCMV INFECTIONS | BOEHRINGER INGELHEIM CA LTD (CA) | 2003-01-15 | — | — | EP | disclosed |
| US-6211170-B1 | Azetidinone derivatives for the treatment of HCMV infections | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2001-04-03 | — | — | US | disclosed |