Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 known ✓ | P07550 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.55 |
| ▸ | LOXL2 | Q9Y4K0 | 7/20 | 0.52 |
| ▸ | ABAT | P80404 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | F11 | P03951 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16472531 | 0.97 | — | — | |
| SCHEMBL27597947 | 0.94 | HRH3 (0.55) | HRH3LOXL2ABATTAAR1CA1 | |
| Water SCHEMBL28264730 | 0.94 | HRH3 (0.55) | HRH3LOXL2ABATTAAR1CA1 | |
| Hydrochloric Acid SCHEMBL28110057 | 0.94 | HRH3 (0.55) | HRH3LOXL2ABATTAAR1CA1 | |
| Hydrochloric Acid SCHEMBL27525172 | 0.94 | HRH3 (0.55) | HRH3LOXL2ABATTAAR1CA1 | |
| Naphthalene SCHEMBL28166813 | 0.85 | LOXL2 (0.52) | HRH3LOXL2ABATTAAR1CA1 | |
| Bromide SCHEMBL29198706 | 0.84 | HRH3 (0.73) | HRH3LOXL2ABATTAAR1CA1 | |
| SCHEMBL15828 | 0.80 | HRH3 (0.79) | HRH3LOXL2ABATTAAR1CA1 | |
| SCHEMBL27238704 | 0.80 | HRH3 (0.79) | HRH3LOXL2ABATTAAR1CA1 | |
| SCHEMBL27818801 | 0.78 | LOXL2 (0.50) | HRH3LOXL2ABATTAAR1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107936056-B | A kind of preparation method of diaryl phosphorus bromine compounds | 河南省科学院化学研究所有限公司 | 2019-07-16 | — | — | CN | claimed |
| CN-107936056-B | A kind of preparation method of diaryl phosphorus bromine compounds | 河南省科学院化学研究所有限公司 | 2019-07-16 | — | — | CN | disclosed |
| CN-107936056-A | A kind of preparation method of diaryl phosphorus bromine compounds | 河南省科学院化学研究所有限公司 | 2018-04-20 | — | — | CN | disclosed |
| CN-102190864-A | Epoxy resin composition for sealing packing of semiconductor, semiconductor device, and manufacturing method thereof | HITACHI CHEMICAL CO LTD | 2011-09-21 | — | — | CN | disclosed |
| CN-101273076-B | Method for producing latent catalyst and epoxy resin composition | SUMITOMO BAKELITE CO | 2011-01-19 | — | — | CN | disclosed |
| CN-101273076-A | Method for producing latent catalyst and epoxy resin composition | SUMITOMO BAKELITE CO (JP) | 2008-09-24 | — | — | CN | disclosed |