⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27491 | 0.83 | TSHR (0.38) | — | |
| SCHEMBL1979374 | 0.77 | — | — | |
| SCHEMBL633226 | 0.75 | TSHR (0.50) | — | |
| SCHEMBL5852713 | 0.75 | VCAM1 (0.43) | — | |
| SCHEMBL2186256 | 0.73 | MMP3 (0.47) | — | |
| SCHEMBL7713 | 0.73 | — | — | |
| SCHEMBL16955503 | 0.72 | TSHR (0.31) | — | |
| SCHEMBL1978751 | 0.72 | — | — | |
| SCHEMBL352200 | 0.72 | — | — | |
| SCHEMBL16953840 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 353 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4146643-B1 | NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES | BAYER AG (DE) | 2024-05-29 | — | — | EP | claimed |
| WO-2024104932-A1 | ARYL THIOETHERS AS HIF-2ALPHA INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2024-05-23 | — | — | WO | claimed |
| CN-112312913-B | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-08 | — | — | CN | claimed |
| WO-2024010784-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS | VIVIDION THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | claimed |
| US-20230373909-A1 | TETRAHYDRO-1H-CYCLOPENTA[CD]INDENE DERIVATIVES AS HYPOXIA INDUCIBLE FACTOR-2(ALPHA) INHIBITORS | NIKANG THERAPEUTICS, INC. | 2023-11-23 | — | — | US | claimed |
| US-20230348432-A1 | NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-02 | — | — | US | claimed |
| US-20230339904-A1 | ISOINDOLINONES, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. | 2023-10-26 | — | — | US | claimed |
| CN-116916900-A | Hypoxia-inducible factor-2 (alpha) inhibitors for the treatment of bladder cancer | 尼坎治疗公司 | 2023-10-20 | — | — | CN | claimed |
| WO-2023069372-A1 | HYPOXIA INDUCIBLE FACTOR-2(ALPHA) INHIBITORS FOR THE TREATMENT OF BLADDER CANCER | NIKANG THERAPEUTICS, INC. (US) | 2023-04-27 | — | — | WO | claimed |
| CN-115996639-A | Novel heteroaryl-triazole compounds as pesticides | 拜耳公司 | 2023-04-21 | — | — | CN | claimed |
| US-20090012034-A1 | Non-Nucleoside reverse transcriptase inhibitors | ROCHE PALO ALTO LLC | 2009-01-08 | — | — | US | claimed |
| WO-2009000663-A1 | UREA AND CARBAMATE DERIVATIVES AS NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-12-31 | — | — | WO | claimed |
| WO-2008145563-A2 | PROCESS FOR PREPARING TRIAZOLONES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-12-04 | — | — | WO | claimed |
| WO-2008145562-A1 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-12-04 | — | — | WO | claimed |
| US-20040186101-A1 | Cyclocarbamate derivatives as progesterone receptor modulators | WYETH | 2004-09-23 | — | — | US | claimed |
| US-6713478-B2 | SUCH AS 8-BROMO-6-(3-CHLORO-4-FLUOROPHENYL)-4,4-DIMETHYL-1,4-DIHYDRO-2H-3,1 -BENZOXAZIN-2-ONE; PROGESTERONE RECEPTOR ANTAGONISTS | WYETH | 2004-03-30 | — | — | US | claimed |
| US-20030216388-A1 | Cyclocarbamate derivatives as progesterone receptor modulators | WYETH | 2003-11-20 | — | — | US | claimed |
| US-6566358-B2 | 1,4-dihydro-benzo(d)oxazin-2-one derivatives useful for treating hormone-dependent neoplastic disease is selected from uterine myometrial fibroids, endometriosis, benign prostatic hypertrophy, carcinomas, and adenocarcinoma | WYETH | 2003-05-20 | — | — | US | claimed |
| US-6509334-B1 | This invention relates to compounds that antagonists of the progesterone receptor, their preparation and utility. Intracellular receptors (IR) form a class of structurally related gene regulators known as \"ligand dependent | AMERICAN HOME PRODUCTS CORPORATION | 2003-01-21 | — | — | US | claimed |
| US-4073783-A | PENICILLINS | PFIZER INC. (US) | 1978-02-14 | — | — | US | claimed |