Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 11/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4668220 | 0.85 | ALOX5 (0.46) | ALOX5MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL4668224 | 0.85 | ALOX5 (0.46) | ALOX5MEN1KMT2AMAPTALDH1A1 | |
| Acetic Acid SCHEMBL4132772 | 0.81 | ALOX5 (0.47) | ALOX5MEN1KMT2AMAPTALDH1A1 | |
| Acetic Acid SCHEMBL4132773 | 0.81 | ALOX5 (0.47) | ALOX5MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL4127367 | 0.78 | ALOX5 (0.51) | ALOX5MEN1KMT2APIM1RAB9A | |
| SCHEMBL4127370 | 0.78 | ALOX5 (0.51) | ALOX5MEN1KMT2APIM1RAB9A | |
| SCHEMBL4138341 | 0.77 | ALOX5 (0.46) | ALOX5MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL4138347 | 0.77 | ALOX5 (0.46) | ALOX5MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL4140263 | 0.77 | ALOX5 (0.47) | ALOX5MEN1KMT2APIM1RAB9A | |
| SCHEMBL4140267 | 0.77 | ALOX5 (0.47) | ALOX5MEN1KMT2APIM1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101268060-A | Thiazolinone and oxazolinone compounds and application thereof as PTP1B inhibitor | TORRENT PHARMACEUTICALS LTD (IN) | 2008-09-17 | — | — | CN | claimed |
| CN-101268060-A | Thiazolinone and oxazolinone compounds and application thereof as PTP1B inhibitor | TORRENT PHARMACEUTICALS LTD (IN) | 2008-09-17 | — | — | CN | disclosed |