Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27739453 | 0.88 | GPBAR1 (0.43) | GPBAR1GAATSHRATMMAPT | |
| SCHEMBL4605598 | 0.85 | GPBAR1 (0.45) | GPBAR1GAATSHRMAPTHTT | |
| SCHEMBL4605164 | 0.84 | GABRA5 (0.49) | GPBAR1GAATSHRMAPTHTT | |
| SCHEMBL27718422 | 0.81 | GPBAR1 (0.46) | GPBAR1GAATSHRMAPTGABRA5 | |
| SCHEMBL4981132 | 0.78 | GABRA5 (0.41) | GPBAR1GAATSHRMAPTHTT | |
| SCHEMBL4981211 | 0.78 | GABRA5 (0.51) | GABRA5KMT2A | |
| SCHEMBL4981836 | 0.77 | GABRA5 (0.55) | GABRA5 | |
| SCHEMBL14188877 | 0.77 | GABRA5 (0.54) | GABRA5 | |
| SCHEMBL4979472 | 0.76 | TSHR (0.51) | GAATSHRATMMAPTHTT | |
| SCHEMBL4979497 | 0.76 | ALDH1A1 (0.49) | TSHRL3MBTL1GABRA5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101277952-A | Isoxazole derivatives | HOFFMANN LA ROCHE (CH) | 2008-10-01 | — | — | CN | disclosed |