Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.69 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | SMO | Q99835 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.49 |
| ▸ | NNMT | P40261 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29074197 | 1.00 | UBE2T (0.69) | UBE2TOPRM1OPRK1ALDH1A1HPGD | |
| SCHEMBL30415822 | 1.00 | UBE2T (0.69) | UBE2TOPRM1OPRK1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL5008434 | 0.98 | UBE2T (0.67) | UBE2TOPRM1OPRK1ALDH1A1HPGD | |
| SCHEMBL30289763 | 0.98 | UBE2T (0.71) | UBE2TOPRM1OPRK1ALDH1A1HPGD | |
| SCHEMBL29475033 | 0.98 | UBE2T (0.71) | UBE2TOPRM1OPRK1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL5010433 | 0.97 | UBE2T (0.69) | UBE2TOPRM1OPRK1ALDH1A1HPGD | |
| SCHEMBL29847287 | 0.87 | UBE2T (0.60) | UBE2TOPRM1OPRK1ALDH1A1HPGD | |
| SCHEMBL27930875 | 0.85 | UBE2T (0.54) | UBE2TOPRM1OPRK1ALDH1A1HPGD | |
| SCHEMBL28694330 | 0.85 | ALDH1A1 (0.64) | UBE2TOPRM1OPRK1ALDH1A1HPGD | |
| SCHEMBL4850532 | 0.85 | UBE2T (0.61) | UBE2TALDH1A1HPGDKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101437800-A | Compounds and compositions as HEDGEHOG pathway modulators | IRM LLC (BM) | 2009-05-20 | — | — | CN | claimed |
| CN-102746285-B | Compounds and compositions as HEDGEHOG pathway modulators | 太阳制药国际公司 | 2022-01-14 | — | — | CN | disclosed |
| CN-101437800-A | Compounds and compositions as HEDGEHOG pathway modulators | IRM LLC (BM) | 2009-05-20 | — | — | CN | disclosed |