Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.71 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.61 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.54 |
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | SMO | Q99835 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NNMT | P40261 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.49 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | JAK1 | P23458 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30289763 | 1.00 | UBE2T (0.71) | UBE2TOPRM1OPRK1ALDH1A1HPGD | |
| SCHEMBL29074197 | 0.98 | UBE2T (0.69) | UBE2TOPRM1OPRK1ALDH1A1HPGD | |
| SCHEMBL27739969 | 0.98 | UBE2T (0.69) | UBE2TOPRM1OPRK1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL5010433 | 0.98 | UBE2T (0.69) | UBE2TOPRM1OPRK1ALDH1A1HPGD | |
| SCHEMBL30415822 | 0.98 | UBE2T (0.69) | UBE2TOPRM1OPRK1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL5008434 | 0.97 | UBE2T (0.67) | UBE2TOPRM1OPRK1ALDH1A1HPGD | |
| SCHEMBL29847287 | 0.89 | UBE2T (0.60) | UBE2TOPRM1OPRK1ALDH1A1HPGD | |
| SCHEMBL27930875 | 0.87 | UBE2T (0.54) | UBE2TOPRM1OPRK1ALDH1A1HPGD | |
| SCHEMBL28694330 | 0.87 | ALDH1A1 (0.64) | UBE2TOPRM1OPRK1ALDH1A1HPGD | |
| SCHEMBL5008448 | 0.85 | UBE2T (0.53) | UBE2TOPRM1OPRK1ALDH1A1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665331-A1 | ALPHA-SYNUCLEIN BINDERS AND METHODS OF USE | Merck Sharp & Dohme LLC (US) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024217344-A1 | NAV1.8 INHIBITORS, PREPARATION METHOD THEREFOR AND USE THEREOF | 中国科学院上海药物研究所 | 2024-10-24 | — | — | WO | disclosed |
| WO-2024173219-A1 | ALPHA-SYNUCLEIN BINDERS AND METHODS OF USE | MERCK SHARP & DOHME LLC (US) | 2024-08-22 | — | — | WO | disclosed |
| CN-118324743-A | Nav1.8 inhibitor and preparation method and application thereof | 中国科学院上海药物研究所 | 2024-07-12 | — | — | CN | disclosed |
| CN-116139138-A | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-115724847-A | 2, 3-dihydroimidazo [1,2-c ] quinazoline substituted derivatives | 拜耳知识产权有限责任公司 | 2023-03-03 | — | — | CN | disclosed |
| CN-110177551-B | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-02-17 | — | — | CN | disclosed |
| CN-105254634-B | 2, 3-dihydroimidazo [1,2-c ] quinazoline substituted derivatives useful in the treatment of hyperproliferative diseases and angiogenesis-related diseases | 拜耳知识产权有限责任公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-109729716-B | PI3K inhibitor combination | 拜耳制药股份公司 | 2022-03-15 | — | — | CN | disclosed |