Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | ELANE | P08246 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | GLS | O94925 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3802279 | 0.76 | POLB (0.39) | GPR3CYP2C19CYP1A2POLBIDO1 | |
| SCHEMBL3532632 | 0.76 | GPR3 (0.36) | GPR3CYP2C19CYP1A2POLBBACE1 | |
| SCHEMBL28079370 | 0.74 | GPR3 (0.34) | GPR3CYP2C19CYP1A2POLBKDM4E | |
| SCHEMBL30599479 | 0.74 | GLS (0.50) | GPR3POLBKDM4EHSD17B10ELANE | |
| SCHEMBL27623423 | 0.74 | KDM4E (0.41) | GPR3CYP2C19CYP1A2POLBBACE1 | |
| SCHEMBL27721238 | 0.74 | GPR3 (0.34) | GPR3CYP2C19CYP1A2POLBIDO1 | |
| SCHEMBL12998307 | 0.74 | KDM4E (0.47) | GPR3CYP2C19POLBKDM4EHSD17B10 | |
| SCHEMBL19798248 | 0.74 | GPR3 (0.34) | GPR3CYP2C19CYP1A2POLBIDO1 | |
| SCHEMBL28150127 | 0.74 | ELANE (0.35) | GPR3CYP2C19CYP1A2POLBIDO1 | |
| SCHEMBL27740479 | 0.74 | ESR1 (0.35) | KDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101282939-A | Diacyl indazole derivatives as lipase and phospholipase inhibitors | SANOFI AVENTIS (FR) | 2008-10-08 | — | — | CN | disclosed |