Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.42 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22036268 | 0.84 | HPGD (0.49) | ALDH1A1OPRK1APPHTR1AADRA2A | |
| SCHEMBL2775887 | 0.81 | STS (0.46) | HPGDMEN1LMNAMAPTKMT2A | |
| SCHEMBL10132293 | 0.81 | ALDH1A1 (0.51) | ALDH1A1OPRK1APPHTR1AADRA2A | |
| SCHEMBL8211106 | 0.78 | GPR119 (0.47) | USP30UCHL1DRD2HTR2AKDM1A | |
| SCHEMBL10132370 | 0.77 | ALDH1A1 (0.50) | USP30UCHL1ALDH1A1NR1H2NR1H3 | |
| SCHEMBL6990776 | 0.77 | STS (0.48) | ALDH1A1OPRK1APPHTR1AADRA2A | |
| SCHEMBL18608053 | 0.77 | MEN1 (0.45) | ALDH1A1OPRK1APPHTR1AADRA2A | |
| SCHEMBL18609579 | 0.77 | MEN1 (0.45) | ALDH1A1OPRK1APPHTR1AADRA2A | |
| SCHEMBL982003 | 0.76 | CHEK1 (0.46) | USP30UCHL1ALDH1A1OPRK1APP | |
| Hydrochloric Acid SCHEMBL27768333 | 0.76 | CHEK1 (0.45) | USP30UCHL1ALDH1A1OPRK1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2241569-B1 | THIENOPYRIDAZINE COMPOUNDS, THEIR PREPARATIONS, PHARMACEUTICAL COMPOSITIONS AND USES | ZHEJIANG MED XINCHANG PHARM (CN) | 2012-05-23 | — | — | EP | disclosed |
| EP-2241569-A1 | THIENOPYRIDAZINE COMPOUNDS, THEIR PREPARATIONS, PHARMACEUTICAL COMPOSITIONS AND USES | Zhejiang Medicine Co., Ltd. Xinchang Pharmaceutical Factory (CN) | 2010-10-20 | — | — | EP | disclosed |