Creatine

Creatine

SCHEMBL2774041

CN(CC(=O)O)C(=N)N.P

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 1/20 0.44
NOS1 P29475 1/20 0.44
NOS2 P35228 1/20 0.44
CA1 P00915 13/20 0.39
CA2 P00918 13/20 0.39
EYA2 O00167 1/20 0.35
APP P05067 1/20 0.35
ACE P12821 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CYP2C19 P33261 1/20 0.34
MVD P53602 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Creatine SCHEMBL21567 0.98
Creatine SCHEMBL4007614 0.98 NOS3 (0.46) NOS3NOS1NOS2CA1CA2
Creatine SCHEMBL27979093 0.98 NOS3 (0.46) NOS3NOS1NOS2CA1CA2
Creatine SCHEMBL30063981 0.98
Creatine SCHEMBL1241423 0.95 NOS3 (0.44) NOS3NOS1NOS2CA1CA2
Creatine SCHEMBL21810557 0.95 NOS3 (0.44) NOS3NOS1NOS2CA1CA2
Creatine SCHEMBL53010 0.95 NOS3 (0.44) NOS3NOS1NOS2CA1CA2
Creatine SCHEMBL20497169 0.95 NOS3 (0.44) NOS3NOS1NOS2CA1CA2
Creatine SCHEMBL21404054 0.95 NOS3 (0.44) NOS3NOS1NOS2CA1CA2
Creatine SCHEMBL5326455 0.95 NOS3 (0.44) NOS3NOS1NOS2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107383090-B A kind of synthesis technology of Creatine Phosphate Sodium 泰山医学院 2019-09-17 CN claimed
CN-109152810-A Methods and compositions for preventing and treating duchenne muscular dystrophy 康德生物医疗技术公司 2019-01-04 CN claimed
CN-107383090-A A kind of synthesis technique of Creatine Phosphate Sodium 泰山医学院 2017-11-24 CN claimed
CN-106011163-A Method for cell-free expression of signal protein and expression system 武汉华美生物工程有限公司 2016-10-12 CN claimed
CN-110408635-A A kind of application of the nucleic acid constructs containing Streptavidin element in protein expression, purifying KANGMA SHANGHAI BIOTECHNOLOGY CO LTD 2019-11-05 CN disclosed
CN-110325641-A The Cell free expression system of energy regeneration based on inorganic polyphosphate 耐特希生物有限公司 2019-10-11 CN disclosed
CN-107383090-B A kind of synthesis technology of Creatine Phosphate Sodium 泰山医学院 2019-09-17 CN disclosed
CN-107383090-B A kind of synthesis technology of Creatine Phosphate Sodium 泰山医学院 2019-09-17 CN disclosed
CN-108949801-B A method of by knocking out nucleic acid enzyme system to regulate and control external biological synthesizing activity 康码(上海)生物科技有限公司 2019-06-14 CN disclosed
CN-109841278-A A method of the screening of coronary disease disease is carried out with angiocarpy mark and rote learning operation method 长庚医疗财团法人林口长庚纪念医院 2019-06-04 CN disclosed
CN-109837293-A A kind of series connection DNA element that can enhance protein synthesis efficiency 康码(上海)生物科技有限公司 2019-06-04 CN disclosed
CN-109154001-A Novel minimal UTR sequences 埃泽瑞斯公司 2019-01-04 CN disclosed
CN-102014980-A Devices and methods for treating central nervous system pathologies UNIV WAKE FOREST HEALTH SCIENCES 2011-04-13 CN disclosed
EP-2237812-A1 DEVICE AND METHOD FOR TREATING CENTRAL NERVOUS SYSTEM PATHOLOGY Wake Forest University Health Sciences (US) 2010-10-13 EP disclosed
CN-101084937-B Ginkgo leaves freezing-dried powder injection and preparation method thereof ZHENBAODAO PHARMACEUTICAL CO LTD HEILONGJIANG PROV 2010-06-30 CN disclosed
US-20090254120-A1 DEVICE AND METHOD FOR TREATING CENTRAL NERVOUS SYSTEM PATHOLOGY WAKE FOREST UNIVERSITY HEALTH SCIENCES 2009-10-08 US disclosed
WO-2009089435-A1 DEVICE AND METHOD FOR TREATING CENTRAL NERVOUS SYSTEM PATHOLOGY WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) 2009-07-16 WO disclosed
CN-101084937-A Ginkgo leaves freezing-dried powder injection and preparation method thereof HEILONGJIANG ZHENBAODAO PHARMA (CN) 2007-12-12 CN disclosed
US-5130119-A Sulfonamide or hydroxy fluorine substituted benzene for medical diagnosis SCHERING AKTIENGESELLSCHAFT (DE) 1992-07-14 US disclosed
US-4959612-A Method of heteronuclear decoupling in magnetic resonance spectroscopy, and device for determining a spectrum U.S. PHILIPS CORPORATION (US) 1990-09-25 US disclosed