Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4606178 | 0.77 | ALDH1A1 (0.57) | ALDH1A1PKMMEN1KMT2AAMY1A | |
| SCHEMBL4606694 | 0.76 | ALDH1A1 (0.60) | ALDH1A1PKMMEN1KMT2AAMY1A | |
| SCHEMBL4027884 | 0.69 | ALDH1A1 (0.44) | ALDH1A1PKMMEN1KMT2AMAPT | |
| SCHEMBL6960006 | 0.69 | ALDH1A1 (0.54) | ALDH1A1PKMMEN1KMT2ATSHR | |
| SCHEMBL6960011 | 0.69 | ALDH1A1 (0.54) | ALDH1A1PKMMEN1KMT2ATSHR | |
| SCHEMBL10746185 | 0.69 | ALDH1A1 (0.70) | ALDH1A1PKMMEN1KMT2AACHE | |
| SCHEMBL11200693 | 0.68 | ALDH1A1 (0.52) | ALDH1A1PKMMEN1KMT2ATSHR | |
| SCHEMBL10925033 | 0.68 | ALDH1A1 (0.50) | ALDH1A1PKMMEN1KMT2AMAPT | |
| SCHEMBL10924766 | 0.67 | ALDH1A1 (0.54) | ALDH1A1PKMMEN1KMT2AMAPT | |
| SCHEMBL8824809 | 0.67 | ALDH1A1 (0.49) | ALDH1A1PKMMEN1KMT2AAMY1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101296911-A | Arylurea derivatives as modulators of chemokine receptor activity | NOVARTIS AG (CH) | 2008-10-29 | — | — | CN | disclosed |