Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | F2R | P25116 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2774058 | 1.00 | NPSR1 (0.44) | NPSR1HCRTR1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL102458 | 0.88 | GAA (0.42) | ALDH1A1KCNK3KCNK9F2RGRIN2B | |
| SCHEMBL2789848 | 0.88 | HCRTR1 (0.50) | NPSR1HCRTR1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL102459 | 0.88 | GAA (0.42) | ALDH1A1KCNK3KCNK9F2RGRIN2B | |
| SCHEMBL2789846 | 0.88 | HCRTR1 (0.50) | NPSR1HCRTR1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL11831818 | 0.78 | NPSR1 (0.40) | NPSR1HCRTR1ALDH1A1HSD17B10MAPT | |
| SCHEMBL16563990 | 0.75 | F2R (0.45) | HCRTR1ALDH1A1KCNK3KCNK9F2R | |
| SCHEMBL16563989 | 0.75 | F2R (0.45) | HCRTR1ALDH1A1KCNK3KCNK9F2R | |
| SCHEMBL23761699 | 0.72 | ANO1 (0.44) | HCRTR1ALDH1A1KCNK3KCNK9F2R | |
| SCHEMBL8653429 | 0.72 | LMNA (0.55) | ALDH1A1HSD17B10MAPTGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2193126-A1 | OXADIAZOLE DIARYL COMPOUNDS | Merck Serono S.A. (CH) | 2010-06-09 | — | — | EP | disclosed |
| WO-2009043890-A1 | OXADIAZOLE DIARYL COMPOUNDS | MERCK SERONO S.A. (CH) | 2009-04-09 | — | — | WO | disclosed |