Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.38 |
| ▸ | NQO1 | P15559 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28307100 | 0.88 | HPGDS (0.52) | HPGDSSLC6A2SLC6A4SLC6A3HTR3A | |
| SCHEMBL28120216 | 0.82 | HPGDS (0.56) | HPGDSPDE3BPDE3ANQO1PDGFRB | |
| SCHEMBL6990269 | 0.79 | HPGDS (0.77) | HPGDSNQO1PDGFRBPDGFRAALDH1A1 | |
| Hydrochloric Acid SCHEMBL29902485 | 0.78 | HPGDS (0.75) | HPGDSNQO1PDGFRBPDGFRAALDH1A1 | |
| SCHEMBL17442542 | 0.76 | HPGDS (0.44) | HPGDSALDH1A1HTTCYP3A4MAP4K4 | |
| SCHEMBL17327692 | 0.74 | HPGDS (0.69) | HPGDSNQO1PDGFRBPDGFRAALDH1A1 | |
| SCHEMBL7447851 | 0.74 | ALDH1A1 (0.53) | ALDH1A1MAPT | |
| SCHEMBL27555688 | 0.73 | HPGDS (0.72) | HPGDSNQO1PDGFRBPDGFRAALDH1A1 | |
| SCHEMBL15753147 | 0.71 | HPGDS (0.47) | HPGDSNQO1ALDH1A1HPGDMEN1 | |
| SCHEMBL29624688 | 0.71 | HPGDS (0.73) | HPGDSNQO1PDGFRBPDGFRAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102743382-A | Methods and compositions for stimulating neurogenesis and inhibiting neuronal degeneration | NEURONASCENT INC | 2012-10-24 | — | — | CN | disclosed |
| CN-101304743-B | Methods and compositions for stimulating neurogenesis and inhibiting neuronal degeneration | NEURONASCENT INC | 2012-09-05 | — | — | CN | disclosed |
| CN-101304743-A | Methods and compositions for stimulating neurogenesis and inhibiting neuronal degeneration | NEURONASCENT INC (US) | 2008-11-12 | — | — | CN | disclosed |