SCHEMBL27740792

SCHEMBL27740792

CC(C)c1cc(Br)cc(C(C)C)c1-c1ncc[nH]1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.41
GABRB1 P18505 1/20 0.41
ADRA2A P08913 5/20 0.41
ADRA2B P18089 4/20 0.41
ADRA2C P18825 4/20 0.41
TAAR1 Q96RJ0 1/20 0.37
NISCH Q9Y2I1 2/20 0.37
P2RX3 P56373 1/20 0.36
P2RX2 Q9UBL9 1/20 0.36
FPR2 P25090 3/20 0.35
MTOR P42345 1/20 0.35
ADK P55263 1/20 0.35
ALDH1A1 P00352 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
SMPD3 Q9NY59 1/20 0.35
PDE4A P27815 1/20 0.33
PDE4B Q07343 1/20 0.33
PDE4C Q08493 1/20 0.33
PDE4D Q08499 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27740794 0.83 GABRA1 (0.41) GABRA1GABRB1ADRA2AADRA2BADRA2C
SCHEMBL2821845 0.79 TAAR1 (0.54) GABRA1GABRB1ADRA2AADRA2BADRA2C
Bromide SCHEMBL31606836 0.77 TAAR1 (0.53) GABRA1GABRB1ADRA2AADRA2BADRA2C
Hydrochloric Acid SCHEMBL28055288 0.77 TAAR1 (0.53) GABRA1GABRB1ADRA2AADRA2BADRA2C
SCHEMBL28275920 0.75 TAAR1 (0.35) ADRA2ATAAR1NISCHP2RX3P2RX2
SCHEMBL28766423 0.75 TAAR1 (0.50) GABRA1GABRB1ADRA2AADRA2BADRA2C
SCHEMBL28021702 0.75 TAAR1 (0.50) GABRA1GABRB1ADRA2AADRA2BADRA2C
SCHEMBL28728517 0.70 NISCH (0.52) ADRA2AADRA2BADRA2CNISCHMTOR
SCHEMBL19769010 0.69 TAAR1 (0.48) ADRA2AADRA2BADRA2CTAAR1NISCH
SCHEMBL9495458 0.67 NISCH (0.54) ADRA2ATAAR1NISCHMTORADK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101282982-B Catalyst for polymerizing cycloolefins LG ELECTRONICS INC 2013-03-27 CN disclosed
CN-101291961-B Polymerization methods using the catalysts LG CHEMICAL LTD 2011-02-16 CN disclosed
CN-101291961-A Polymerization methods using the catalysts LG CHEMICAL LTD (KR) 2008-10-22 CN disclosed
CN-101282982-A Catalyst for polymerizing cycloolefins LG CHEMICAL LTD (KR) 2008-10-08 CN disclosed