Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A known ✓ | P08913 | 4/20 | 0.49 |
| ▸ | ADRA2B known ✓ | P18089 | 3/20 | 0.49 |
| ▸ | ADRA2C known ✓ | P18825 | 3/20 | 0.49 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.36 |
| ▸ | GABRA1 known ✓ | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 known ✓ | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 known ✓ | P18507 | 1/20 | 0.36 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.36 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.36 |
| ▸ | HTR2C known ✓ | P28335 | 1/20 | 0.36 |
| ▸ | GABRB3 known ✓ | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 known ✓ | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 known ✓ | P34903 | 1/20 | 0.36 |
| ▸ | HTR2B known ✓ | P41595 | 1/20 | 0.36 |
| ▸ | GABRA2 known ✓ | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 known ✓ | P47870 | 1/20 | 0.36 |
| ▸ | GABRA4 known ✓ | P48169 | 1/20 | 0.36 |
| ▸ | GABRA6 known ✓ | Q16445 | 1/20 | 0.36 |
| ▸ | CYP19A1 known ✓ | P11511 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2821845 | 0.98 | TAAR1 (0.54) | TAAR1ADRA2AADRA2BADRA2CNISCH | |
| Bromide SCHEMBL31606836 | 0.96 | TAAR1 (0.53) | TAAR1ADRA2AADRA2BADRA2CNISCH | |
| SCHEMBL28021702 | 0.93 | TAAR1 (0.50) | TAAR1ADRA2AADRA2BADRA2CNISCH | |
| SCHEMBL28766423 | 0.93 | TAAR1 (0.50) | TAAR1ADRA2AADRA2BADRA2CNISCH | |
| SCHEMBL19769010 | 0.87 | TAAR1 (0.48) | TAAR1ADRA2AADRA2BADRA2CNISCH | |
| SCHEMBL8043932 | 0.79 | ADRA2A (0.49) | TAAR1ADRA2AADRA2BADRA2CNISCH | |
| SCHEMBL27733927 | 0.78 | TAAR1 (0.49) | TAAR1ADRA2AADRA2BADRA2CNISCH | |
| SCHEMBL27740792 | 0.77 | GABRA1 (0.41) | TAAR1ADRA2AADRA2BADRA2CNISCH | |
| SCHEMBL27740794 | 0.77 | GABRA1 (0.41) | TAAR1ADRA2AADRA2BADRA2CNISCH | |
| Hydrochloric Acid SCHEMBL29265356 | 0.76 | NISCH (0.50) | TAAR1ADRA2AADRA2BADRA2CNISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184540-A | Preparation method of 2-fluoro-5-formylbenzonitrile | 福建福瑞明德药业有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-117843428-A | endo/exo 3, 4-disubstituted tricyclo [4.2.1.0 2,5 ]Process for preparing non-3, 7-diene compound | 湖南师范大学 | 2024-04-09 | — | — | CN | claimed |
| CN-116903434-A | Copper-catalyzed method for preparing difluoromethyl olefin by hydrodefluorination of trifluoromethyl olefin | 凯美克(上海)医药科技有限公司 | 2023-10-20 | — | — | CN | claimed |
| CN-112920145-B | Method for synthesizing 2, 5-furandicarboxylic acid by visible light catalysis | 新乡学院 | 2023-06-20 | — | — | CN | claimed |
| CN-116217352-A | Method for preparing cannabigerol and analogues thereof | 上海中医药大学 | 2023-06-06 | — | — | CN | claimed |
| CN-116023241-A | Phenanthrene ketone compound and preparation method thereof | 龙岩学院 | 2023-04-28 | — | — | CN | claimed |
| CN-112457440-B | Boron functionalized o-carborane-styrene polymer and preparation method thereof | 西南科技大学 | 2023-03-24 | — | — | CN | claimed |
| CN-113929620-B | Preparation method of stable isotope labeled boscalid internal standard reagent | 谱同生物医药科技(常州)有限公司 | 2022-12-13 | — | — | CN | claimed |
| CN-113336784-B | 3-substituted benzofluorenone or 3-substituted naphthofluorenone derivatives and synthesis method thereof | 上海大学 | 2022-11-18 | — | — | CN | claimed |
| CN-115141072-A | Preparation method of biphenyl and derivatives thereof | 江苏师范大学 | 2022-10-04 | — | — | CN | claimed |
| CN-113336784-A | 3-substituted benzofluorenone or 3-substituted naphthofluorenone derivatives and synthesis method thereof | 上海大学 | 2021-09-03 | — | — | CN | claimed |
| CN-112457440-A | Boron functionalized o-carborane-styrene polymer and preparation method thereof | 西南科技大学 | 2021-03-09 | — | — | CN | claimed |
| CN-108554456-B | Application of rare earth imidazolium salt compound as catalyst | 苏州大学 | 2021-02-12 | — | — | CN | claimed |
| CN-109020966-B | Method for preparing cosmetic additive 2- (benzofuran-2-yl) benzoxazole | 常州大学 | 2020-02-14 | — | — | CN | claimed |
| CN-102659919-B | A kind of synthetic method of Velcade | HEFEI UNIVERSITY OF TECHNOLOGY (CN) | 2016-03-30 | — | — | CN | claimed |
| CN-101648145-A | Method for preparing asymmetric substituted aryl compound or terphenyl derivative by one-pot tandem reaction of functionalized imidazole salt and palladium salt | UNIV ZHEJIANG | 2010-02-17 | — | — | CN | claimed |
| US-20250179572-A1 | Photoactive Compounds and Methods for Biomolecule Detection and Sequencing | VIBRANT HOLDINGS, LLC | 2025-06-05 | — | — | US | disclosed |
| CN-115260366-B | Catalyst system for forming multiblock copolymers | 陶氏环球技术有限责任公司 | 2025-01-28 | — | — | CN | disclosed |
| CN-102659919-B | A kind of synthetic method of Velcade | HEFEI UNIVERSITY OF TECHNOLOGY (CN) | 2016-03-30 | — | — | CN | disclosed |
| CN-101648145-A | Method for preparing asymmetric substituted aryl compound or terphenyl derivative by one-pot tandem reaction of functionalized imidazole salt and palladium salt | UNIV ZHEJIANG | 2010-02-17 | — | — | CN | disclosed |