Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL67832 | 0.87 | RIPK1 (0.60) | RIPK1CYP1A2CYP2D6CYP2C19LMNA | |
| SCHEMBL6473350 | 0.76 | RIPK1 (0.48) | RIPK1CYP1A2CYP2D6CYP2C19LMNA | |
| SCHEMBL6473402 | 0.76 | RIPK1 (0.47) | RIPK1CYP1A2CYP2D6CYP2C19LMNA | |
| SCHEMBL662742 | 0.74 | RIPK1 (0.64) | RIPK1POLBKMT2AMEN1TAAR1 | |
| SCHEMBL2634610 | 0.74 | RIPK1 (0.64) | RIPK1LMNAKMT2AMEN1HTT | |
| SCHEMBL5361863 | 0.74 | AOC3 (0.53) | RIPK1 | |
| SCHEMBL9802185 | 0.72 | CYP1A2 (0.61) | CYP1A2CYP2D6CYP2C19TAAR1 | |
| SCHEMBL1577575 | 0.72 | CYP1A2 (0.61) | CYP1A2CYP2D6CYP2C19TAAR1 | |
| SCHEMBL2442972 | 0.72 | CYP1A2 (0.61) | CYP1A2CYP2D6CYP2C19TAAR1 | |
| SCHEMBL5599017 | 0.72 | CYP1A2 (0.61) | CYP1A2CYP2D6CYP2C19TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101296897-A | PPAR-modulating biaromatic compounds | GALDERMA RES & DEV (FR) | 2008-10-29 | — | — | CN | disclosed |