Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 11/20 | 0.65 |
| ▸ | ERBB2 | P04626 | 6/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.54 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2687295 | 0.90 | EGFR (0.78) | EGFRERBB2CA1CA2MEN1 | |
| SCHEMBL27778197 | 0.89 | MEN1 (0.62) | EGFRERBB2CA1CA2MEN1 | |
| SCHEMBL19471298 | 0.89 | EGFR (0.67) | EGFRERBB2CA1CA2MEN1 | |
| SCHEMBL31429970 | 0.87 | EGFR (0.74) | EGFRERBB2CA1CA2MEN1 | |
| SCHEMBL27955200 | 0.84 | MEN1 (0.77) | EGFRERBB2CA1CA2MEN1 | |
| SCHEMBL27799194 | 0.83 | CA1 (0.67) | EGFRCA1CA2MEN1KMT2A | |
| SCHEMBL23052315 | 0.81 | EGFR (0.69) | EGFRERBB2CA1CA2MEN1 | |
| SCHEMBL23052047 | 0.81 | EGFR (0.69) | EGFRERBB2CA1CA2MEN1 | |
| SCHEMBL13680429 | 0.80 | EGFR (0.71) | EGFRERBB2CA1CA2MEN1 | |
| SCHEMBL13680425 | 0.80 | EGFR (0.75) | EGFRERBB2CA1CA2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101429162-A | Method for producing 1-phenyl-3,5-di-substituted aryl-2-pyrazoline | HUAIYIN TEACHERS COLLEGE (CN) | 2009-05-13 | — | — | CN | disclosed |