Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 11/20 | 0.69 |
| ▸ | ERBB2 | P04626 | 8/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | ERBB3 | P21860 | 2/20 | 0.56 |
| ▸ | KDR | P35968 | 2/20 | 0.56 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23052315 | 1.00 | EGFR (0.69) | EGFRERBB2LMNAPKMCA1 | |
| SCHEMBL15301033 | 0.94 | EGFR (0.62) | EGFRERBB2LMNAERBB3KDR | |
| SCHEMBL15301281 | 0.91 | MEN1 (0.60) | EGFRERBB2CA1CA2ERBB3 | |
| SCHEMBL15300830 | 0.91 | EGFR (0.65) | EGFRERBB2LMNACA1CA2 | |
| SCHEMBL2687295 | 0.90 | EGFR (0.78) | EGFRERBB2LMNACA1CA2 | |
| SCHEMBL15301173 | 0.89 | PRKCZ (0.64) | EGFRERBB2LMNACA1CA2 | |
| SCHEMBL15301362 | 0.89 | MEN1 (0.60) | EGFRERBB2LMNACA1CA2 | |
| SCHEMBL18040117 | 0.87 | PRKCZ (0.62) | EGFRERBB2LMNAPKMERBB3 | |
| SCHEMBL31429970 | 0.87 | EGFR (0.74) | EGFRERBB2LMNACA1CA2 | |
| SCHEMBL15301210 | 0.86 | MEN1 (0.64) | EGFRERBB2LMNACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021039824-A1 | RNA METHYLTRANSFERASE INHIBITOR, SCREENING METHOD THEREFOR, ANTI-CANCER AGENT EFFICACY ASSESSMENT MARKER, AND KIT FOR EFFECTIVELY PREDICTING FTSJ1 INHIBITOR | 国立大学法人 岡山大学 | 2021-03-04 | — | — | WO | disclosed |