Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.67 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.67 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2687295 | 0.91 | EGFR (0.78) | EGFRERBB2CA1CA2MEN1 | |
| SCHEMBL27741002 | 0.89 | EGFR (0.65) | EGFRERBB2CA1CA2MEN1 | |
| SCHEMBL31429970 | 0.88 | EGFR (0.74) | EGFRERBB2CA1CA2MEN1 | |
| SCHEMBL19471296 | 0.88 | GAA (0.73) | EGFRERBB2CA1CA2MEN1 | |
| SCHEMBL27955200 | 0.85 | MEN1 (0.77) | EGFRERBB2CA1CA2MEN1 | |
| SCHEMBL19471302 | 0.84 | MEN1 (0.55) | EGFRERBB2MEN1KMT2AGAA | |
| SCHEMBL23052047 | 0.84 | EGFR (0.69) | EGFRERBB2CA1CA2MEN1 | |
| SCHEMBL23052315 | 0.84 | EGFR (0.69) | EGFRERBB2CA1CA2MEN1 | |
| SCHEMBL13680429 | 0.81 | EGFR (0.71) | EGFRERBB2CA1CA2MEN1 | |
| SCHEMBL14338087 | 0.81 | MEN1 (0.69) | EGFRERBB2CA1CA2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10800966-B2 | Organic scintillators derived from pyrazoline | CLEMSON UNIVERSITY RESEARCH FOUNDATION (US) | 2020-10-13 | — | — | US | disclosed |
| US-10800966-B2 | Organic scintillators derived from pyrazoline | CLEMSON UNIVERSITY RESEARCH FOUNDATION (US) | 2020-10-13 | — | — | US | disclosed |
| US-20170306220-A1 | Organic Scintillators Derived from Pyrazoline | DEFENSE THREAT REDUCTION AGENCY, US DOD | 2017-10-26 | — | — | US | disclosed |
| US-20170306220-A1 | Organic Scintillators Derived from Pyrazoline | DEFENSE THREAT REDUCTION AGENCY, US DOD | 2017-10-26 | — | — | US | disclosed |
| US-20170306220-A1 | Organic Scintillators Derived from Pyrazoline | DEFENSE THREAT REDUCTION AGENCY, US DOD | 2017-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10800966-B2 | Organic scintillators derived from pyrazoline | SELENOI, SCLY, GPX4 | EGFR 3697/4885ERBB2 2442/4885CA1 4479/4885 |
| US-20170306220-A1 | Organic Scintillators Derived from Pyrazoline | SELENOI, SCLY, GPX4 | EGFR 3697/4885ERBB2 2442/4885CA1 4479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.