Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 7/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29747084 | 0.83 | DGAT1 (0.39) | DGAT1MAPT | |
| SCHEMBL2564153 | 0.81 | DGAT1 (0.37) | DGAT1KLKB1LMNAMAPTMEN1 | |
| SCHEMBL31070090 | 0.81 | KLKB1 (0.35) | DGAT1KLKB1MAPTNPC1 | |
| SCHEMBL25194791 | 0.81 | DGAT1 (0.42) | DGAT1MAPTNPC1 | |
| SCHEMBL31512683 | 0.81 | DGAT1 (0.38) | DGAT1MAPT | |
| SCHEMBL31512681 | 0.81 | DGAT1 (0.38) | DGAT1MAPT | |
| SCHEMBL14738023 | 0.80 | DGAT1 (0.42) | DGAT1KLKB1MAPTPTPN1NPC1 | |
| SCHEMBL31512721 | 0.78 | DGAT1 (0.45) | DGAT1MAPTPTPN1 | |
| SCHEMBL27741648 | 0.78 | DGAT1 (0.36) | DGAT1MAPTPIN1KMT2A | |
| SCHEMBL18209976 | 0.77 | DGAT1 (0.38) | DGAT1KLKB1LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101432287-A | Pyrrolopyrimidine derivatives as HSP90 inhibitors | VERNALIS R&D LTD (GB) | 2009-05-13 | — | — | CN | disclosed |