Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 5/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 13/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25194791 | 0.87 | DGAT1 (0.42) | DGAT1MAPT | |
| SCHEMBL31512681 | 0.87 | DGAT1 (0.38) | DGAT1MAPT | |
| SCHEMBL31512683 | 0.87 | DGAT1 (0.38) | DGAT1MAPT | |
| SCHEMBL27741648 | 0.84 | DGAT1 (0.36) | DGAT1MAPT | |
| SCHEMBL31512721 | 0.84 | DGAT1 (0.45) | DGAT1LRRK2MAPT | |
| SCHEMBL27741684 | 0.83 | DGAT1 (0.38) | DGAT1MAPT | |
| SCHEMBL31512728 | 0.83 | DGAT1 (0.36) | DGAT1LRRK2MAPT | |
| SCHEMBL29409874 | 0.78 | DGAT1 (0.36) | DGAT1MAPT | |
| SCHEMBL29409887 | 0.78 | DGAT1 (0.36) | DGAT1MAPT | |
| SCHEMBL2018451 | 0.78 | DGAT1 (0.36) | DGAT1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023222005-A1 | AROMATIC HETEROCYCLIC COMPOUND AND INTERMEDIATE, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 上海翊石医药科技有限公司 | 2023-11-23 | — | — | WO | disclosed |
| WO-2022139386-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | 주식회사 비투에스바이오 | 2022-06-30 | — | — | WO | disclosed |