Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4422093 | 0.86 | GPR119 (0.75) | GPR119ALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL27742207 | 0.86 | GPR119 (0.57) | GPR119ALDH1A1NPC1RAB9ANAMPT | |
| SCHEMBL4609180 | 0.86 | GPR119 (0.58) | GPR119ALDH1A1NPC1RAB9ANAMPT | |
| SCHEMBL27721316 | 0.81 | GPR119 (0.51) | GPR119ALDH1A1NPC1RAB9ANAMPT | |
| SCHEMBL4415731 | 0.81 | GPR119 (0.57) | GPR119ALDH1A1NPC1RAB9ANAMPT | |
| SCHEMBL27742198 | 0.81 | GPR119 (0.61) | GPR119ALDH1A1NPC1RAB9ANAMPT | |
| SCHEMBL13598241 | 0.81 | GPR119 (0.61) | GPR119ALDH1A1NPC1RAB9ANAAA | |
| SCHEMBL27721530 | 0.80 | GPR119 (0.52) | GPR119ALDH1A1NPC1RAB9ANAMPT | |
| SCHEMBL27721339 | 0.80 | GPR119 (0.52) | GPR119ALDH1A1NPC1RAB9ANAMPT | |
| SCHEMBL14640645 | 0.78 | NAAA (0.44) | GPR119ALDH1A1NPC1RAB9ANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101287729-A | GPCR agonists | PROSIDION LTD (GB) | 2008-10-15 | — | — | CN | disclosed |