Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | NAAA | Q02083 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL27413134 | 0.94 | KDM4E (0.61) | ALDH1A1KDM4EHPGDNAAAGAA | |
| Salicylic Acid SCHEMBL27587665 | 0.92 | KDM4E (0.59) | ALDH1A1KDM4EHPGDNAAAGAA | |
| Tetrahexylammonium SCHEMBL17641341 | 0.84 | ALDH1A1 (0.58) | ALDH1A1KDM4EHPGDNAAAGAA | |
| Salicylic Acid SCHEMBL27304494 | 0.84 | ALDH1A1 (0.58) | ALDH1A1KDM4EHPGDNAAAGAA | |
| Salicylic Acid SCHEMBL27409901 | 0.84 | ALDH1A1 (0.58) | ALDH1A1KDM4EHPGDNAAAGAA | |
| Salicylic Acid SCHEMBL18109167 | 0.84 | ALDH1A1 (0.58) | ALDH1A1KDM4EHPGDNAAAGAA | |
| Salicylic Acid SCHEMBL28152897 | 0.84 | ALDH1A1 (0.58) | ALDH1A1KDM4EHPGDNAAAGAA | |
| Palmitic Acid SCHEMBL11047096 | 0.83 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDNAAAMEN1 | |
| Salicylic Acid SCHEMBL28588841 | 0.83 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDNAAAGAA | |
| Stearic Acid SCHEMBL10695822 | 0.83 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDNAAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101451087-B | Method for preparing lubricating oil metal detergent | PETROCHINA CO LTD | 2011-01-12 | — | — | CN | disclosed |
| CN-101451087-A | Method for preparing lubricating oil metal detergent | PETROCHINA CO LTD (CN) | 2009-06-10 | — | — | CN | disclosed |