Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 6/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL27413134 | 0.98 | KDM4E (0.61) | KDM4EALDH1A1HPGDNAAAGAA | |
| Salicylic Acid SCHEMBL27743166 | 0.92 | ALDH1A1 (0.58) | KDM4EALDH1A1HPGDNAAAGAA | |
| Salicylic Acid SCHEMBL8013642 | 0.82 | KDM4E (0.61) | KDM4EALDH1A1HPGDNAAAGAA | |
| Salicylic Acid SCHEMBL5526971 | 0.82 | KDM4E (0.61) | KDM4EALDH1A1HPGDNAAAGAA | |
| Salicylic Acid SCHEMBL3362988 | 0.82 | KDM4E (0.61) | KDM4EALDH1A1HPGDNAAAGAA | |
| Salicylic Acid SCHEMBL406693 | 0.81 | KDM4E (0.59) | KDM4EALDH1A1HPGDNAAAGAA | |
| Salicylic Acid SCHEMBL666959 | 0.81 | KDM4E (0.59) | KDM4EALDH1A1HPGDNAAAGAA | |
| Tetrabuthylammonium SCHEMBL107740 | 0.81 | KDM4E (0.59) | KDM4EALDH1A1HPGDNAAAGAA | |
| Salicylic Acid SCHEMBL8099142 | 0.81 | KDM4E (0.59) | KDM4EALDH1A1HPGDNAAAGAA | |
| Salicylic Acid SCHEMBL2810943 | 0.81 | KDM4E (0.59) | KDM4EALDH1A1HPGDNAAAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1396151-A | Tert-butyl salicylic acid complex and its preparing process | DINGLONG CHEMICAL CO LTD HUBEI (CN) | 2003-02-12 | — | — | CN | disclosed |