SCHEMBL27743705

SCHEMBL27743705

C=C(C)C(=O)OC(CC)C[Si](C)(OCC)OCC

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.39
TSHR P16473 3/20 0.33
ALDH1A1 P00352 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27566958 0.87 THRB (0.35) THRBTSHRALDH1A1
SCHEMBL27733723 0.85 ALDH1A1 (0.36) THRBTSHRALDH1A1
SCHEMBL81024 0.85 THRB (0.36) THRBTSHRALDH1A1
SCHEMBL9301845 0.84 TSHR (0.33) THRBTSHRALDH1A1
SCHEMBL2878662 0.82 THRB (0.40) THRBTSHRALDH1A1
SCHEMBL440616 0.78 TSHR (0.45) THRBTSHRALDH1A1
SCHEMBL9301836 0.77 TSHR (0.33) THRBTSHRALDH1A1
SCHEMBL9303049 0.77 TSHR (0.33) THRBTSHRALDH1A1
SCHEMBL81665 0.77 ALDH1A1 (0.38) THRBTSHRALDH1A1
Ammonia Solution, Strong SCHEMBL27784925 0.77 TSHR (0.43) THRBTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101501088-B Silicone acrylate hybrid compositions DOW CORNING CORP. (US) 2011-11-30 CN claimed
CN-101501088-A Silicone acrylate hybrid compositions DOW CORNING (US) 2009-08-05 CN claimed
CN-102803311-B Procatalyst composition with adamantane and method DOW GLOBAL TECHNOLOGIES INC 2014-07-02 CN disclosed
CN-101952339-B Coating agent having high scratch resistance and high weathering resistance BASF COATINGS AG 2013-09-25 CN disclosed
CN-101300319-B Alpha-ethoxysilane-modified polymers, production and use thereof HENKEL KGAA 2013-03-13 CN disclosed
CN-102803311-A Procatalyst Composition With Adamantane And Method DOW GLOBAL TECHNOLOGIES INC 2012-11-28 CN disclosed
CN-101952337-B Coating agent with high scratch resistance and weather resistance BASF COATINGS AG 2012-11-14 CN disclosed
CN-101583643-B Coating composition with high scratch resistance and weather stability BASF COATINGS AG 2012-11-07 CN disclosed
CN-101563382-B Coating agents having high scratch resistance and weathering stability BASF COATINGS AG 2012-09-19 CN disclosed
CN-101772552-B Crosslinkable substances based on organosilicon compounds WACKER CHEMIE AG 2012-09-05 CN disclosed
CN-101501088-B Silicone acrylate hybrid compositions DOW CORNING CORP. (US) 2011-11-30 CN disclosed
CN-101952338-A Coating agent with high scratch resistance and weather resistance BASF COATINGS AG 2011-01-19 CN disclosed
CN-101952339-A Coating agent having high scratch resistance and high weathering resistance BASF COATINGS AG 2011-01-19 CN disclosed
CN-101952337-A Coating agent with high scratch resistance and weather resistance BASF COATINGS AG 2011-01-19 CN disclosed
CN-101772552-A Crosslinkable substances based on organosilicon compounds WACKER CHEMIE AG 2010-07-07 CN disclosed
CN-101583643-A Coating composition with high scratch resistance and weather stability BASF COATINGS AG (DE) 2009-11-18 CN disclosed
CN-101563382-A Coating agents having high scratch resistance and weathering stability BASF COATINGS AG (DE) 2009-10-21 CN disclosed
CN-101501088-A Silicone acrylate hybrid compositions DOW CORNING (US) 2009-08-05 CN disclosed
CN-101300319-A Alpha-ethoxysilane-modified polymers, production and use thereof HENKEL KGAA (DE) 2008-11-05 CN disclosed