Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.49 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL989199 | 0.82 | KMT2A (0.48) | S1PR2S1PR1S1PR3LPAR2HSD17B10 | |
| SCHEMBL12988089 | 0.79 | MEN1 (0.47) | HSD17B10TSHRALOX15PTGDR2TDP1 | |
| SCHEMBL6183033 | 0.78 | MAPT (0.51) | PKMMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL3714744 | 0.76 | PKM (0.66) | PKMTSHRPTGDR2TDP1MEN1 | |
| SCHEMBL5940467 | 0.76 | MAPT (0.64) | TDP1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL1615073 | 0.76 | PKM (0.70) | PKMTSHRPTGDR2TDP1MAPT | |
| SCHEMBL4975454 | 0.75 | PKM (0.64) | PKMHSD17B10TSHRALOX15PTGDR2 | |
| SCHEMBL5502944 | 0.74 | PKM (0.68) | PKMHSD17B10TSHRALOX15PTGDR2 | |
| SCHEMBL2112042 | 0.73 | PKM (1.00) | PKMPTGDR2TDP1MAPTALDH1A1 | |
| SCHEMBL1369311 | 0.73 | TDP1 (0.70) | PKMTSHRPTGDR2TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010102154-A2 | BIARYL OXYACETIC ACID COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2010-09-10 | — | — | WO | disclosed |