Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | GAA | P10253 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | GMNN | O75496 | 1/20 | 0.52 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrazine SCHEMBL29155863 | 0.96 | GAA (0.53) | ALDH1A1GAATSHRLMNAKMT2A | |
| SCHEMBL28508904 | 0.84 | GAA (0.61) | ALDH1A1GAATSHRLMNAKMT2A | |
| SCHEMBL9194052 | 0.84 | ALDH1A1 (0.53) | ALDH1A1GAATSHRLMNAKMT2A | |
| SCHEMBL38555 | 0.84 | ALDH1A1 (0.53) | ALDH1A1GAATSHRLMNAKMT2A | |
| SCHEMBL11308767 | 0.83 | ALDH1A1 (0.57) | ALDH1A1GAATSHRLMNAKMT2A | |
| SCHEMBL9519034 | 0.82 | GAA (0.54) | ALDH1A1GAATSHRLMNAKMT2A | |
| SCHEMBL6965645 | 0.82 | ALDH1A1 (0.55) | ALDH1A1GAATSHRLMNAKMT2A | |
| SCHEMBL9014505 | 0.82 | ALDH1A1 (0.52) | ALDH1A1GAATSHRLMNAKMT2A | |
| SCHEMBL8310747 | 0.82 | ALDH1A1 (0.56) | ALDH1A1GAATSHRLMNAKMT2A | |
| Ammonia Solution, Strong SCHEMBL3948778 | 0.82 | ALDH1A1 (0.52) | ALDH1A1GAATSHRLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108700689-A | Synthetic resin laminated body with photochromic characteristic and use its lens | 三菱瓦斯化学株式会社 | 2018-10-23 | — | — | CN | disclosed |
| CN-103842432-B | Radical polymerization type acrylic resin composition, water-repellent material composition, laminate, and method for producing same | 三菱化学株式会社 | 2018-03-16 | — | — | CN | disclosed |
| CN-107463076-A | Image forming apparatus | 富士施乐株式会社 | 2017-12-12 | — | — | CN | disclosed |
| CN-103168080-B | Curable composition | CEMEDINE CO.,LTD. (JP) | 2015-10-21 | — | — | CN | disclosed |
| CN-104945861-A | Polyester resin composition | MITSUBISHI CHEM CORP | 2015-09-30 | — | — | CN | disclosed |
| CN-104903406-A | Resin composition, triazole compound, optical film, polarizing plate, optical lens, circularly polarizing plate, and image display device | KONICA MINOLTA INC | 2015-09-09 | — | — | CN | disclosed |
| CN-103339195-B | Polyester resin composition | MITSUBISHI CHEMICAL CORP. (JP) | 2015-08-12 | — | — | CN | disclosed |
| CN-102300925-B | Curable composition | CEMEDINE CO LTD | 2014-06-18 | — | — | CN | disclosed |
| CN-103339195-A | Polyester resin composition | MITSUBISHI CHEM CORP | 2013-10-02 | — | — | CN | disclosed |
| US-20120252931-A1 | STABILIZER COMPOSITION FOR FILLED POLYMERS AND NANOCOMPOSITES | BASF SE (DE) | 2012-10-04 | — | — | US | disclosed |
| US-7232812-B2 | Substituted azetidine compounds, their preparation and use as medicaments | LABORATORIOS DE DR. ESTEVE S.A. (ES) | 2007-06-19 | — | — | US | disclosed |
| US-7232812-B2 | Substituted azetidine compounds, their preparation and use as medicaments | LABORATORIOS DE DR. ESTEVE S.A. (ES) | 2007-06-19 | — | — | US | disclosed |
| US-20070093469-A1 | Substituted azetidine compounds as cyclooxygenase-1-cyclooxygenase-2 inhibitors, and their preparation and use as medicaments | LABORATORIOS DEL DR. ESTEVE S.A (ES) | 2007-04-26 | — | — | US | disclosed |
| US-20070093469-A1 | Substituted azetidine compounds as cyclooxygenase-1-cyclooxygenase-2 inhibitors, and their preparation and use as medicaments | LABORATORIOS DEL DR. ESTEVE S.A (ES) | 2007-04-26 | — | — | US | disclosed |
| EP-1379514-A2 | 5-MEMBERED HETEROCYCLES, PREPARATION AND APPLICATION THEREOF AS MEDICAMENTS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2004-01-14 | — | — | EP | disclosed |
| WO-2002083656-A2 | 5-MEMBERED HETEROCYCLES, PREPARATION AND USE THEREOF AS MAO INHIBITORS AND LIPID PEROXIDATION INHIBITORS, PREPARATION THEREOF AND USE THEREOF AS MEDICAMENTS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2002-10-24 | — | — | WO | disclosed |
| EP-0276805-B1 | Substituted 3-phenyl-7H-thiazolo[3,2-b][1,2,4]triazin-7-ones, processes for their preparation, medicaments containing them and their use as well as some of the intermediates obtained during the preparation of said compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-17 | — | — | EP | disclosed |
| EP-0280868-B1 | IMIDAZO- AND TRIAZOLOTHIADIAZINES, PROCESS FOR THEIR PREPARATION, MEDICAMENTS CONTAINING THEM AND THEIR USE AS WELL AS SOME OF THE INTERMEDIATES OBTAINED DURING THE PREPARATION OF SAID COMPOUNDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-06-17 | — | — | EP | disclosed |
| EP-0280868-A2 | Imidazo- and triazolothiadiazines, process for their preparation, medicaments containing them and their use as well as some of the intermediates obtained during the preparation of said compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-09-07 | — | — | EP | disclosed |
| EP-0276805-A2 | Substituted 3-phenyl-7H-thiazolo[3,2-b][1,2,4]triazin-7-ones, processes for their preparation, medicaments containing them and their use as well as some of the intermediates obtained during the preparation of said compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070093469-A1 | Substituted azetidine compounds as cyclooxygenase-1-cyclooxygenase-2 inhibitors, and their preparation and use as medicaments | PTGS1, PTGS2, PTGES2 | ALDH1A1 52/4885GAA 614/4885TSHR 4185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.