SCHEMBL277442

SCHEMBL277442

CCCCCCC(CO)C(=O)OCC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CPB2 Q96IY4 2/20 0.53
CA2 P00918 2/20 0.48
LMNA P02545 2/20 0.47
ZDHHC7 Q9NXF8 1/20 0.46
CA1 P00915 1/20 0.44
GRIK1 P39086 2/20 0.43
GRIK2 Q13002 2/20 0.43
GPR84 Q9NQS5 3/20 0.42
FFAR1 O14842 1/20 0.42
KDM4E B2RXH2 1/20 0.42
DUSP3 P51452 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
MAPT P10636 2/20 0.42
MAPK1 P28482 1/20 0.42
LCK P06239 1/20 0.41
PPARD Q03181 1/20 0.41
ZDHHC20 Q5W0Z9 1/20 0.41
ZDHHC2 Q9UIJ5 1/20 0.41
SLC1A2 P43004 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL319980 1.00 CPB2 (0.53) CPB2CA2LMNAZDHHC7CA1
Methyl Alcohol SCHEMBL7668985 0.98 CPB2 (0.51) CPB2CA2LMNAZDHHC7CA1
Ammonia Solution, Strong SCHEMBL5121318 0.98 CPB2 (0.51) CPB2CA2LMNAZDHHC7CA1
SCHEMBL3845206 0.98 CPB2 (0.50) CPB2CA2LMNAZDHHC7CA1
Acetic Acid SCHEMBL3260364 0.95 CPB2 (0.49) CPB2CA2LMNAZDHHC7CA1
Ethyl Acetate SCHEMBL1279632 0.93 CPB2 (0.47) CPB2CA2LMNAZDHHC7CA1
Ethyl Acetate SCHEMBL5064725 0.93 CPB2 (0.47) CPB2CA2LMNAZDHHC7CA1
SCHEMBL3176263 0.92 CA2 (0.52) CPB2CA2CA1KDM4EDUSP3
Ethyl Acetate SCHEMBL17005456 0.90 CPB2 (0.45) CPB2CA2LMNAZDHHC7GRIK1
Ethyl Acetate SCHEMBL17699277 0.90 CPB2 (0.45) CPB2CA2LMNAZDHHC7GRIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1035 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3782986-B1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICALS CO (JP) 2024-07-10 EP disclosed
CN-113307772-B Human plasma kallikrein inhibitors 拜奥克里斯特制药公司 2024-06-28 CN disclosed
EP-4389750-A1 NUCLEOSIDE DERIVATIVES AND PRODRUGS THEREOF HAVING VIRAL GROWTH INHIBITORY ACTION Shionogi & Co., Ltd. (JP) 2024-06-26 EP disclosed
US-11964943-B2 3,5-diarylidenyl-n-substituted-piperid-4-one-derived inhibitors of Stat3 pathway activity and uses thereof KIAKOS KONSTANTINOS (AT) 2024-04-23 US disclosed
CN-112313210-B Photochromic indeno-fused naphthopyran compounds with reduced temperature dependence 光学转变有限公司 2024-03-15 CN disclosed
CN-111918863-B Heterocyclic compounds 武田药品工业株式会社 2024-01-05 CN disclosed
US-20230117295-A1 NITROGEN CONTAINING HETEROCYCLES AS CDK12 INHIBITORS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-04-20 US disclosed
US-11584737-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-02-21 US disclosed
WO-2023014049-A1 NOVEL PYRROLOPYRIMIDINE DERIVATIVE, METHOD OF PREPARING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING METABOLIC LIVER DISEASE 한국화학연구원 2023-02-09 WO disclosed
WO-2023278827-A1 3-IODOPROPYL-1,2,3-TRIAZOL-1-YL, 3-BROMOPROPYL-1,2,3-TRIAZOL-1-YL, AND DERIVATIVES FOR USES IN LABELING EMORY UNIVERSITY (US) 2023-01-05 WO disclosed
US-4351843-A LOWERING BLOOD GLUCOSE PFIZER INC. (US) 1982-09-28 US disclosed
US-4347187-A Process for preparing 5-aroyl 1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acids and novel intermediates therein SYNTEX (U.S.A.) INC. (US) 1982-08-31 US disclosed
US-4347186-A Process for preparing 5-aroyl 1,2-dihydro-3-H pyrrolo[1,2-a]pyrrole-1-carboxylic acids and novel intermediates therein SYNTEX (U.S.A.) INC. (US) 1982-08-31 US disclosed
US-4282242-A HYPOGLYCEMIC AGENTS PFIZER INC. (US) 1981-08-04 US disclosed
US-4238622-A D,L-2-Amino-4-(2-aminoethoxy)-trans-but-3-enoic acid derivatives HOFFMANN-LA ROCHE INC. (US) 1980-12-09 US disclosed
US-4058551-A PROSTAGLANDINS THE UPJOHN COMPANY (US) 1977-11-15 US disclosed
US-4042606-A PROSTAGLANDIN ENANTIOMORPHS THE UPJOHN COMPANY (US) 1977-08-16 US disclosed
US-3962289-A PROSTAGLANDINS THE UPJOHN COMPANY (US) 1976-06-08 US disclosed
US-3932486-A GASTRIC SECRETION INHIBITORS, ANTISPASMODIC, ANTIASTHMATIC, HYPOTENSIVE THE UPJOHN COMPANY (US) 1976-01-13 US disclosed
US-3931281-A PROSTAGLANDINS THE UPJOHN COMPANY (US) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230117295-A1 NITROGEN CONTAINING HETEROCYCLES AS CDK12 INHIBITORS CDK1, CDK12, CDK15 CPB2 1265/4885CA2 1739/4885LMNA 1082/4885
US-11964943-B2 3,5-diarylidenyl-n-substituted-piperid-4-one-derived inhibitors of Stat3 pathway activity and uses thereof STAT3, JAK2, STAT6 CPB2 3524/4885CA2 2894/4885LMNA 3396/4885
US-11584737-B2 Heterocyclic compound CDK12, CDK1, CDK15 CPB2 1186/4885CA2 1518/4885LMNA 1157/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.