Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.53 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4469107 | 0.87 | GPR119 (0.53) | GPR119NPBWR1MCHR1HPGD | |
| SCHEMBL2538047 | 0.87 | GPR119 (0.53) | GPR119NPBWR1MCHR1HPGDPIK3CD | |
| SCHEMBL3343105 | 0.86 | GPR119 (0.52) | GPR119NPBWR1MCHR1 | |
| SCHEMBL20303652 | 0.86 | GPR119 (0.52) | GPR119NPBWR1MCHR1HPGD | |
| SCHEMBL4714125 | 0.85 | GPR119 (0.62) | GPR119 | |
| SCHEMBL29716446 | 0.85 | GPR119 (0.53) | GPR119NPBWR1MCHR1HPGD | |
| SCHEMBL2774875 | 0.85 | GPR119 (0.51) | GPR119NPBWR1MCHR1HPGDPIK3CD | |
| SCHEMBL2774561 | 0.85 | GPR119 (0.51) | GPR119NPBWR1MCHR1 | |
| SCHEMBL19147635 | 0.84 | GPR119 (0.53) | GPR119NPBWR1MCHR1 | |
| SCHEMBL19147575 | 0.84 | GPR119 (0.50) | GPR119NPBWR1MCHR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110053933-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-03-03 | — | — | US | disclosed |
| EP-2258697-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2010-12-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053933-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | F12, F2, C3AR1 | GPR119 1336/4885NPBWR1 2278/4885MCHR1 2946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.