Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENTPD2 | Q9Y5L3 | 3/20 | 0.38 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.37 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.35 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.35 |
| ▸ | UMPS | P11172 | 1/20 | 0.34 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ENTPD1 | P49961 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28773057 | 0.87 | P2RY2 (0.39) | ENTPD2P2RY2P2RY14P2RY4P2RY6 | |
| SCHEMBL13455737 | 0.85 | SLC28A1 (0.48) | P2RY2UMPS | |
| SCHEMBL12143136 | 0.85 | SLC28A1 (0.48) | P2RY2UMPS | |
| SCHEMBL1362548 | 0.85 | SLC28A1 (0.48) | P2RY2UMPS | |
| SCHEMBL1362545 | 0.85 | SLC28A1 (0.48) | P2RY2UMPS | |
| SCHEMBL27744571 | 0.82 | TYMP (0.39) | ENTPD2P2RY2P2RY14ALDH1A1KDM4E | |
| SCHEMBL1361957 | 0.80 | UMPS (0.58) | P2RY2P2RY14P2RY4P2RY6UMPS | |
| SCHEMBL12143135 | 0.80 | UMPS (0.58) | P2RY2P2RY14P2RY4P2RY6UMPS | |
| SCHEMBL27723833 | 0.77 | HIF1A (0.40) | P2RY2P2RY14ALDH1A1KMT2AP2RY4 | |
| SCHEMBL27744472 | 0.77 | HASPIN (0.38) | ENTPD2P2RY2P2RY14P2RY4P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101321775-A | ODCASE inhibitors for the treatment of malaria | UNIV HEALTH NETWORK (CA) | 2008-12-10 | — | — | CN | claimed |
| CN-101321775-B | ODCASE inhibitors for the treatment of malaria | UNIV HEALTH NETWORK | 2012-05-23 | — | — | CN | disclosed |
| CN-101321775-A | ODCASE inhibitors for the treatment of malaria | UNIV HEALTH NETWORK (CA) | 2008-12-10 | — | — | CN | disclosed |