Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 2/20 | 0.69 |
| ▸ | DGKA | P23743 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PRKCA | P17252 | 3/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.49 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.49 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10877193 | 0.98 | PAM (0.71) | PAMDGKATSHRMAPTLMNA | |
| SCHEMBL10881317 | 0.98 | PAM (0.71) | PAMDGKATSHRMAPTLMNA | |
| SCHEMBL15722717 | 0.98 | PAM (0.71) | PAMDGKATSHRMAPTLMNA | |
| SCHEMBL4617303 | 0.98 | PAM (0.71) | PAMDGKATSHRMAPTLMNA | |
| SCHEMBL7802315 | 0.98 | PAM (0.71) | PAMDGKATSHRMAPTLMNA | |
| SCHEMBL10439746 | 0.96 | PAM (0.68) | PAMDGKATSHRMAPTLMNA | |
| SCHEMBL2553776 | 0.90 | PAM (0.59) | PAMDGKATSHRMAPTLMNA | |
| SCHEMBL11837895 | 0.89 | PAM (0.57) | PAMDGKATSHRMAPTLMNA | |
| SCHEMBL21585321 | 0.88 | DGKA (0.60) | PAMDGKAMAPTLMNADUSP3 | |
| SCHEMBL18230733 | 0.86 | PAM (0.71) | PAMDGKATSHRMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100506234-C | Pharmaceutical composition for the treatment of ulcerative colitis and Crohn's disease comprising 5-aminosalicylic acid | FERRING BV (NL) | 2009-07-01 | — | — | CN | disclosed |