Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPPL2A | Q8TCT8 | 3/20 | 0.50 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.47 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.47 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 13/20 | 0.44 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | MMP14 | P50281 | 2/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8021812 | 0.88 | SPPL2A (0.50) | SPPL2APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2579683 | 0.88 | SPPL2A (0.50) | SPPL2APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2578310 | 0.87 | SPPL2A (0.50) | SPPL2APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2581195 | 0.86 | TAS2R14 (0.51) | SPPL2APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2577597 | 0.84 | TAS2R14 (0.50) | SPPL2APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2576905 | 0.83 | MAPK1 (0.49) | SPPL2APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6473313 | 0.83 | SPPL2A (0.50) | SPPL2APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL15157850 | 0.83 | TAS2R14 (0.49) | SPPL2APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3575750 | 0.83 | TAS2R14 (0.49) | SPPL2ARORCTAS2R14MMP2MMP13 | |
| SCHEMBL7618676 | 0.83 | ALDH1A1 (0.59) | SPPL2APSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101304987-A | Aminophenylsulfonamide derivatives as HIV protease inhibitor | TIBOTEC PHARM LTD (IE) | 2008-11-12 | — | — | CN | disclosed |