Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | FDPS | P14324 | 18/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CASP2 | P42575 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18211778 | 0.89 | MEN1 (0.55) | MEN1KMT2ASMN1; SMN2HSP90AA1FDPS | |
| SCHEMBL22667793 | 0.89 | MEN1 (0.55) | MEN1KMT2ASMN1; SMN2HSP90AA1FDPS | |
| Bromide SCHEMBL28197087 | 0.84 | MEN1 (0.57) | MEN1KMT2ASMN1; SMN2HSP90AA1FDPS | |
| Bicarbonate SCHEMBL23698567 | 0.84 | MEN1 (0.63) | MEN1KMT2ASMN1; SMN2HSP90AA1FDPS | |
| Bicarbonate SCHEMBL23698489 | 0.84 | MEN1 (0.63) | MEN1KMT2ASMN1; SMN2HSP90AA1FDPS | |
| Bicarbonate SCHEMBL23698565 | 0.84 | MEN1 (0.63) | MEN1KMT2ASMN1; SMN2HSP90AA1FDPS | |
| Bicarbonate SCHEMBL23698472 | 0.84 | MEN1 (0.63) | MEN1KMT2ASMN1; SMN2HSP90AA1FDPS | |
| Bicarbonate SCHEMBL23698494 | 0.84 | MEN1 (0.63) | MEN1KMT2ASMN1; SMN2HSP90AA1FDPS | |
| Bicarbonate SCHEMBL23698395 | 0.84 | MEN1 (0.63) | MEN1KMT2ASMN1; SMN2HSP90AA1FDPS | |
| Bicarbonate SCHEMBL23698486 | 0.84 | MEN1 (0.63) | MEN1KMT2ASMN1; SMN2HSP90AA1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101471166-A | Method for modifying magnetic nano particle by functionalized ionic liquid | LANZHOU INST CHEM PHYSICS CAS (CN) | 2009-07-01 | — | — | CN | disclosed |