Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 11/20 | 0.47 |
| ▸ | DCUN1D1 | Q96GG9 | 11/20 | 0.47 |
| ▸ | SOAT2 | O75908 | 2/20 | 0.45 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12169907 | 0.79 | PPARG (0.51) | UBE2MDCUN1D1THRBPPARGPPARD | |
| Hydrochloric Acid SCHEMBL1449278 | 0.78 | PPARG (0.50) | UBE2MDCUN1D1THRBPPARGPPARD | |
| Hydrochloric Acid SCHEMBL1449214 | 0.77 | UBE2M (0.45) | UBE2MDCUN1D1 | |
| SCHEMBL1448948 | 0.76 | PPARG (0.49) | UBE2MDCUN1D1SOAT1PPARGPPARD | |
| Hydrochloric Acid SCHEMBL1448931 | 0.76 | PPARG (0.48) | UBE2MDCUN1D1THRBPPARGPPARD | |
| Hydrochloric Acid SCHEMBL841464 | 0.75 | PPARG (0.49) | UBE2MDCUN1D1SOAT1PPARGPPARD | |
| Hydrochloric Acid SCHEMBL1448893 | 0.75 | TP53 (0.44) | UBE2MDCUN1D1THRBPPARGPPARD | |
| SCHEMBL1980528 | 0.75 | PPARG (0.47) | UBE2MDCUN1D1THRBPPARGPPARD | |
| Hydrochloric Acid SCHEMBL842269 | 0.75 | PPARG (0.46) | UBE2MDCUN1D1THRBPPARGPPARD | |
| SCHEMBL1981970 | 0.75 | PPARG (0.46) | UBE2MDCUN1D1THRBPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101928284-A | Nitrogen-containing heterocyclic derivatives and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO | 2010-12-29 | — | — | CN | disclosed |
| CN-1787996-B | Nitrogen-containing heterocyclic derivative and drug containing the same as active ingredient | ONO PHARMACEUTICAL CO | 2010-06-16 | — | — | CN | disclosed |
| CN-101333185-A | Nitrogen-containing heterocyclic derivatives and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO (JP) | 2008-12-31 | — | — | CN | disclosed |
| CN-101333186-A | Nitrogen-containing heterocyclic derivatives and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO (JP) | 2008-12-31 | — | — | CN | disclosed |