Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.46 |
| ▸ | UBE2M | P61081 | 3/20 | 0.45 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL841464 | 0.99 | PPARG (0.49) | PPARGPPARDPPARASLC6A2SLC6A4 | |
| SCHEMBL3805770 | 0.82 | DCUN1D1 (0.41) | SLC6A2SLC6A4UBE2MDCUN1D1 | |
| SCHEMBL9269080 | 0.81 | PPARG (0.53) | PPARGPPARDPPARAHTTSOAT1 | |
| SCHEMBL9269084 | 0.81 | PPARG (0.53) | PPARGPPARDPPARAHTTSOAT1 | |
| Trifluoroacetic Acid SCHEMBL6731864 | 0.79 | PPARG (0.59) | PPARGPPARDPPARASLC6A2SLC6A4 | |
| SCHEMBL27266162 | 0.78 | PPARG (0.57) | PPARGPPARDPPARAHTTUBE2M | |
| SCHEMBL9260551 | 0.77 | PPARG (0.67) | PPARGPPARDPPARAHTTSOAT1 | |
| SCHEMBL9269044 | 0.77 | SOAT1 (0.46) | PPARGPPARDPPARASOAT1UBE2M | |
| SCHEMBL27745186 | 0.76 | UBE2M (0.47) | PPARGPPARDPPARASOAT1UBE2M | |
| SCHEMBL12169907 | 0.75 | PPARG (0.51) | PPARGPPARDPPARAUBE2MDCUN1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385040-A1 | Nitrogen-containing heterocyclic derivatives and drugs containing the same as the active ingredient | ONO Pharmaceutical Co., Ltd. (JP) | 2011-11-09 | — | — | EP | disclosed |
| US-7910741-B2 | Nitrogen-containing heterocyclic derivatives and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2011-03-22 | — | — | US | disclosed |
| US-20060178399-A1 | Nitrogen-containing heterocyclic derivatives and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-08-10 | — | — | US | disclosed |
| EP-1604981-A1 | NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-12-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060178399-A1 | Nitrogen-containing heterocyclic derivatives and drugs containing the same as the active ingredient | HLA-DRB1, ELANE, MMP8 | PPARG 1738/4885PPARD 2320/4885PPARA 3359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.