Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CCR5 | P51681 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1449444 | 0.84 | KMT2A (0.68) | SMN1; SMN2TP53KMT2AMEN1TSHR | |
| Hydrochloric Acid SCHEMBL1449371 | 0.84 | HRH3 (0.48) | ACHEHRH3SMN1; SMN2TP53L3MBTL1 | |
| SCHEMBL27724377 | 0.84 | KDM4E (0.68) | ACHEHRH3SMN1; SMN2KMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL1448697 | 0.83 | TP53 (0.49) | HRH3SMN1; SMN2TP53KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL1449365 | 0.83 | CCR5 (0.49) | ACHEHRH3SMN1; SMN2TP53KMT2A | |
| Hydrochloric Acid SCHEMBL1449121 | 0.83 | SMN1; SMN2 (0.59) | SMN1; SMN2TP53KMT2AMEN1TSHR | |
| SCHEMBL27745212 | 0.81 | ACHE (0.60) | ACHESMN1; SMN2TSHRLTA4HKDM4E | |
| SCHEMBL14456815 | 0.81 | TP53 (0.60) | SMN1; SMN2TP53KMT2AMEN1TSHR | |
| SCHEMBL27724385 | 0.80 | CCR5 (0.53) | ACHEHRH3SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL10947749 | 0.80 | KMT2A (0.76) | SMN1; SMN2TP53KMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101928284-A | Nitrogen-containing heterocyclic derivatives and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO | 2010-12-29 | — | — | CN | disclosed |
| CN-1787996-B | Nitrogen-containing heterocyclic derivative and drug containing the same as active ingredient | ONO PHARMACEUTICAL CO | 2010-06-16 | — | — | CN | disclosed |
| CN-101333185-A | Nitrogen-containing heterocyclic derivatives and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO (JP) | 2008-12-31 | — | — | CN | disclosed |
| CN-101333186-A | Nitrogen-containing heterocyclic derivatives and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO (JP) | 2008-12-31 | — | — | CN | disclosed |