Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3144115 | 0.85 | HPGD (0.44) | KMT2ALMNAALDH1A1MAPTHPGD | |
| SCHEMBL20074228 | 0.82 | TDP1 (0.50) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL18097798 | 0.80 | EGLN1 (0.44) | KMT2AALKBH1GAA | |
| SCHEMBL16939923 | 0.78 | KMT2A (0.58) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL5267233 | 0.76 | MAPT (0.42) | KMT2ALMNAALDH1A1MAPTHPGD | |
| SCHEMBL19991918 | 0.75 | TDP1 (0.54) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL21559739 | 0.75 | TDP1 (0.54) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL27985786 | 0.72 | BAZ2B (0.42) | KMT2AMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5269260 | 0.72 | ALDH1A1 (0.40) | TDP1KMT2AALDH1A1MAPTHPGD | |
| Benzyl Benzoate SCHEMBL3038 | 0.71 | KMT2A (1.00) | TDP1KMT2ASLC6A2SLC6A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101405275-B | Triazolone Derivatives | EISAI R&D MAN CO LTD | 2011-11-09 | — | — | CN | disclosed |
| CN-101405275-A | Triazolone Derivatives | EISAI R&D MAN CO LTD (JP) | 2009-04-08 | — | — | CN | disclosed |