Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14487048 | 0.85 | BRD4 (0.43) | KDM4EKMT2AMAPTPTGER4KDM5A | |
| SCHEMBL2723759 | 0.81 | LCK (0.41) | KDM4EKDM5AKDM4CKDM5BPOLB | |
| SCHEMBL23367117 | 0.81 | KDM5A (0.41) | KDM4EMAPTPTGER4KDM5AKDM4C | |
| SCHEMBL31539885 | 0.80 | CYP1A2 (0.41) | ALDH1A1KMT2AMAPTPTGER4KDM5A | |
| SCHEMBL17324739 | 0.80 | KDM5A (0.42) | KDM4EALDH1A1GAAKMT2AMAPT | |
| SCHEMBL1563562 | 0.80 | KDM5A (0.48) | KDM4EALDH1A1MAPTPTGER4KDM5A | |
| Hydrochloric Acid SCHEMBL23354423 | 0.79 | KDM5A (0.40) | KDM4EMAPTPTGER4KDM5AKDM4C | |
| SCHEMBL1562180 | 0.79 | ALDH1A1 (0.49) | KDM4EALDH1A1KMT2AKDM5AKDM4C | |
| SCHEMBL3589934 | 0.78 | KDM5A (0.41) | KDM4EMAPTPTGER4KDM5AKDM4C | |
| Methane SCHEMBL27733031 | 0.78 | KDM5A (0.47) | KDM4EALDH1A1MAPTPTGER4KDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101466703-A | Heterocyclic GABA-alpha subtype selective receptor modulators | HOFFMANN LA ROCHE (CH) | 2009-06-24 | — | — | CN | disclosed |